XENON ANESTHESIA IN PEDIATRIC DENTAL INTERVENTIONS

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Introduction. Therapeutic dental manipulations in smaller children are usually done under general anesthesia and sedation using inhalation anesthetics due to their high psychoemotional lability. Xenon (inert gas) is of particular interest among inhalation anesthetic agents due to its unique pharmacological properties such as hypnotic and analgesic effect, lack of toxicity, organ protective properties, etc. Purpose is to estimate adequacy, safety and comfort with anesthesia in pediatric dentistry. Materials and methods. 30 children (18 boys and 12 girls) were involved in an open, prospective, randomized study. They obtained dental treatment for caries and pulpitis. Sevoflurane 8% and concentration of 60–70% xenon with О2 was given to induce anesthesia. Anesthesia adequacy, safety and comfort were estimated based on hemodynamics data, BIS index, concentrations of sevoflurane and xenon in the anesthetic gas, recovery time, rate of agitation, nausea and vomiting. Results. The study demonstrated safety of xenon gas anesthesia in pediatric dentistry. The estimated values were within the reference range. Following anesthesia, recovery occurred after 30 minutes, no single case of postanesthesia agitation, nausea and vomiting was noted. Conclusion. Xenon provides for high effectiveness and safety of anesthesia in pediatric dentistry. The results show that further studies are reasonable.

作者简介

V. Lazarev

“Pirogov Russian National Research Medical University”, Moscow

编辑信件的主要联系方式.
Email: lazarev_vv@inbox.ru
Dr. Sci (Med), Professor, head of Department of pediatric anesthesiology and intensive therapy 俄罗斯联邦

D. Khaliullin

LLC “Dental Forte Elit”: Russian Federation; Naberezhnye Chelny, Naberezhnochelninsky Avenue 10B, Republic of Tatarstan

Email: dr170489@yandex.ru
Anesthesiologist resuscitator 俄罗斯联邦

R. Gabdrafikov

LLC “Dental Forte Elit”: Russian Federation; Naberezhnye Chelny, Naberezhnochelninsky Avenue 10B, Republic of Tatarstan

Email: gendirector@dental-forte.ru
Dentist, chief physician of dental Forte Elite 俄罗斯联邦

D. Koshcheev

LLC “Dental Forte Elit”: Russian Federation; Naberezhnye Chelny, Naberezhnochelninsky Avenue 10B, Republic of Tatarstan

Email: dvkoshceev@gmail.com
Anesthesiologist resuscitator 俄罗斯联邦

E. Gracheva

LLC “Dental Forte Elit”: Russian Federation; Naberezhnye Chelny, Naberezhnochelninsky Avenue 10B, Republic of Tatarstan

Email: murzic_elen@icloud.com
Dentist 俄罗斯联邦

参考

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版权所有 © Lazarev V.V., Khaliullin D.M., Gabdrafikov R.R., Koshcheev D.V., Gracheva E.S., 2019

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