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Extracorporeal hemocorrection in treatment of meningococcal septic shock in children
- Authors: Serednyakov K.V.1, Lobzin Y.V.1
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Affiliations:
- Children’s Clinical Research Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia
- Issue: Vol 9, No 2 (2019)
- Pages: 35-40
- Section: Original Study Articles
- Submitted: 15.08.2019
- Accepted: 15.08.2019
- Published: 15.08.2019
- URL: https://rps-journal.ru/jour/article/view/544
- DOI: https://doi.org/10.30946/2219-4061-2019-9-2-35-40
- ID: 544
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Abstract
Purpose: to estimate the effectiveness of extracorporeal hemocorrection in treatment of refractory meningococcal septic shock in children.
Methods: patients with generalized form of meningococcal infection, multi-organ system failure and refractory septic shock admitted to the resuscitation department of Children’s Clinical Research Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia underwent extracorporeal hemocorrection (polymyxin adsorption, continuous veno-venous hemofiltration, continuous veno-venous hemodiafiltration). MultiFiltrate apparatus was used (Fresenius Medical Care, Germany).
Results: application of extracorporeal hemocorrection technique in the therapy of refractory meningococcal septic shock reduced the mortality from 44.4% to 25%.
Conclusion: effectiveness of extracorporeal hemocorrection when treating patients with refractory meningococcal septic shock is established. A small number of examined patients is a limitation of the study.
About the authors
Konstantin V. Serednyakov
Children’s Clinical Research Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia
Author for correspondence.
Email: spbny@yahoo.com
Head of ICU; Assistant of the Department of anesthesiology – resuscitation and emergency pediatrics of St. Petersburg pediatric medical University
Prof. Popov st. 9, St. Petersburg, Russia, 197022; phone: +7(911)134–11–21
РоссияYuri V. Lobzin
Children’s Clinical Research Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia
Email: niidi@niidi.ru
Dr. Sci (Med), Professor, Director of “Children’s Clinical Research Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia”; head of the Department of infectious diseases “North-Western state medical University named after I. I. Mechnikov”, honored scientist of the Russian Federation, General of medical service, academician of RAS
Prof. Popov st. 9, St. Petersburg, Russia, 197022
РоссияReferences
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