STRUCTURAL CHANGES IN THE INTESTINAL WALL IN IMPLEMENTATION OF THE SYNDROME OF INTESTINAL DYSMOTILITY IN CHILDREN WITH GASTROSCHISIS

S. Babuch; Бабуч Станислав Иванович; K. Tika; Тика Константин; V. Petrovich; Петрович Виржил; L. Sinitsina; Синицина Лилия; A. Zhalbe; Жалбэ Александр; I. Negru; Негру Ион

doi:10.17816/psaic286

STRUCTURAL CHANGES IN THE INTESTINAL WALL IN IMPLEMENTATION OF THE SYNDROME OF INTESTINAL DYSMOTILITY IN CHILDREN WITH GASTROSCHISIS

Authors: Babuch S.¹, Tika K.², Petrovich V.³, Sinitsina L.³, Zhalbe A.¹, Negru I.¹
Affiliations:
1. Nikolai Testemitsanu State University of Medicine & Pharmacy
2. Ovidius University, Constanta
3. Public Health Establishment the Institute of Mother and Child
Issue: Vol 6, No 4 (2016)
Pages: 13-19
Section: Original Study Articles
Submitted: 10.06.2017
Accepted: 10.06.2017
Published: 10.12.2016
URL: https://rps-journal.ru/jour/article/view/286
DOI: https://doi.org/10.17816/psaic286
ID: 286

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Abstract

The authors presented the results of histopathological and immunohistochemical studies using autopsy material (22 newborns who died of gastroschisis). According to the results, in all the cases inflammation of the parietal and visceral peritoneum were of productive, proliferative and fibroplastic origin. In the majority of cases, an acute purulent inflammation with formation of abscesses at the level of the eviscerated intestinal loops was revealed.

In some cases the acute inflammation process was manifested through leukocytic erosive and abscessed inflammatory exudative fibrinous lesions at the level of the parietal and visceral peritoneum involving the entire intestinal wall in the process. The presence of only one mainly circular muscular layer was a peculiar feature found in the eviscerated intestinal loops with the external muscular layer undergoing regional hypoplasia or aplasia.

Results of the conducted study helped the authors to determine the combination of neuromuscular structural changes of the eviscerated intestinal loops and find the relation of the implementation of the intestinal motility stable disturbances in newborns with gastroschisis.

Keywords

gastroschisis, intestinal dysfunction, morphopathology

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STRUCTURAL CHANGES IN THE INTESTINAL WALL IN IMPLEMENTATION OF THE SYNDROME OF INTESTINAL DYSMOTILITY IN CHILDREN WITH GASTROSCHISIS

Full Text

Abstract

Keywords

About the authors

S. Babuch

K. Tika

V. Petrovich

L. Sinitsina

A. Zhalbe

I. Negru

References

Supplementary files

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