Abstract
The authors carried out 226 managements of patients with complicated nephrolithiasis in the age from 1 to 15 years. The risk factors of nephrolithiasis in 87% of cases were maternal diseases, related marriages and various pathologies aggravating the primary condition. Urinary tract anomalies were found in 35.8% of cases. In 61.5% of cases excretory urography showed kidney dysfunction. Calculous pyelonephritis (up to 81.7%) was the most frequent complication, each second child (49.7%) had calculous hydronephrosis. In 86.1 % of early childhood patients nephrolithiasis was observed on the background of somatic and urological pathologies. Intraoperative incisional biopsy allowed to define the criteria of combined kidney injury by hydromechanical and pyelonephritic processes, and also various dysplastic changes of kidney parenchyma.