Cardiovascular complications of COVID-associated multisystem inflammatory syndrome in an infant: A case report

Multisystem inflammatory syndrome is an extremely severe form of coronavirus infection in children, which characterized by systemic hyperinflammation with multiple organ failure. In some cases, cardiovascular complications are reported, including myocardial dysfunction, myocardial ischemia, shock, arrhythmias, coronaritis and coronary artery aneurysms. Although the incidence of coronavirus infection has decreased, patient mortality from multisystem inflammatory syndrome remains high. A clinical case of COVID-associated multisystem inflammatory syndrome in an infant is presented. Since admission, the patient with a high titer of immunoglobulin G with SARS-CoV-2 showed signs of hyperinflammation with subsequent development of pericarditis and myocardial dysfunction associated with prolonged bilateral pneumonia. Coronaritis and aneurysm of the left coronary artery were diagnosed. The patient had a long history of reduced global contractile function and high levels of myocardial damage markers requiring prolonged inotropic support and use of cardiac glycosides. Later, paroxysmal tachycardia developed in addition to cardiovascular complications. Comprehensive management of the disease and early detection of complications resulted in a favorable outcome.