ESTIMATING THE EFFECTIVENESS OF SURGICAL TREATMENT OF CHILDREN WITH THRYOID NEOPLASMS
- Authors: Grachev N.S.1, Vorozhtsov I.N.1, Babaskina N.V.1, Iaremenko Е.I.1
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Affiliations:
- Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
- Issue: Vol 8, No 2 (2018)
- Pages: 33-47
- Section: Original Study Articles
- Submitted: 09.10.2018
- Accepted: 09.10.2018
- Published: 10.06.2018
- URL: https://rps-journal.ru/jour/article/view/427
- DOI: https://doi.org/10.30946/2219-4061-2018-8-2-33-47
- ID: 427
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Full Text
Abstract
Aim. To estimate the effectiveness of the developed design of perioperative examination of patients and surgery of children and adolescents with thyroid neoplasms.
Materials and methods. The data of surgical treatment and perioperative control of 70 patients’ condition from 2012 to July 2017 were presented. The features of perioperative control included prevention of postoperative hypoparathrosis, use of ACR TI-RADS system to interpret the thyroid ultrasound findings as the first line diagnosis of a malignant neoplasm and intraoperative electrophysiological neuromonitoring of the laryngeal nerves. The follow-up was 1 to 56 months. The quality of life was estimated using a questionnaire.
Results. The basic risk factors of an intraoperative injury to the recurrent laryngeal nerve, postoperative hypocalcemia and hypoparathyrosis were found during the study. The disease duration and aggressive course and a number of surgeries in a patient significantly decrease their life quality (p<0.05).
Conclusions. Comparison of quality of life indicators before and after a surgery and popula tion indicators of healthy adolescents revealed the advantage of using the developed scheme of perioperative control of surgical treatment of thyroid neoplasms in children and adolescents.
About the authors
N. S. Grachev
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
Email: nick-grachev@yandex.ru
ORCID iD: 0000-0002-4451-3233
Nikolai S. Grachev – PhD, Head of the Department of Oncology and Pediatric Surgery
117997, Moscow, ul. Samory Mashel 1
РоссияI. N. Vorozhtsov
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
Email: Dr.Vorozhtsov@gmail.com
ORCID iD: 0000-0002-3932-6257
Igor N. Vorozhtsov – Junior Researcher, Head and Neck Surgery Department, reconstructive-plastic surgery
117997, Moscow, ul. Samory Mashel 1
РоссияN. V. Babaskina
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
Email: nbabaskina@bk.ru
ORCID iD: 0000-0003-4264-1423
Natalya V. Babaskina – Oncologist of oncology and pediatric surgery department
117997, Moscow, ul. Samory Mashel 1
РоссияЕ. Iu. Iaremenko
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
Author for correspondence.
Email: yareme@me.com
ORCID iD: 0000-0003-1196-5070
Ekaterina Iu. Iaremenko – Senior Laboratory Assistant of the Department of Head and Neck Surgery with reconstructive-plastic surgery
117997, Moscow, ul. Samory Mashel 1
РоссияReferences
- Гостимский А. В., Романчишен А. Ф. Проблемы диагностики и хирургического лечения больных раком щитовидной железы в детском и подростковом возрасте // Онкохирургия. 2011. 4 (3): с. 55–62.
- Романчишен А. Ф., Thompson G. B. Сравнительные результаты лечения детей и подростков, страдавших раком щитовидной железы, в Центре эндокринной хирургии Санкт-Петербурга и в Клинике Мейо // Педиатр. 2015. 6 (1): с. 38–43.
- Andrea Corrias. Thyroid Nodules in Pediatrics: Which Ones Can Be Left Alone. Which Ones Must be Investigated. When and How // J Clin Res Pediatr Endocrinol. 2013. 5 (1): p. 57–69. doi: 10.4274/jcrpe.853.
- Gary L. Francis, Andrew J. Bauer, Peter Angelos, Salvatore Benvenga, Janete M. Cerutti, Catherine A. Dinauer, Jill Hamilton, Ian D. Hay, Markus Luster, Marguerite T. Parisi, Marianna Rachmiel, Geoffrey B. Thompson, Shunichi Yamashita. Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2015. 25 (7):716–59 doi: 10.1089/thy.2014.0460.
- Румянцев П. О. Интраоперационный нейромониторинг в тиреоидной хирургии // Эндокринная хирургия. 2013. 3: с. 32–40.
- Bergenfelz A., Kristoffersson A., Mårtensson H., Reihnér E., Wallin G., Lausen I. Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients. Langenbecks Archives Of Surgery. 2008. 393 (5): p. 667–673. doi: 10.1007/s00423‑008‑0366-7.
- Wong K. P., Wong C. K., Lang B. H. Systematic review and meta-analysis on intra-operative neuro-monitoring in high-risk thyroidectomy. International journal of surgery. 2017. 38: p. 21–30. doi: 10.1016/j.ijsu.2016.12.039.
- Asari R., Kaczirek K., Scheuba C., Niederle B. Hypoparathyroidism after total thyroidectomy: A prospective study. Archives of Surgery. 2008. 143 (2): p. 132–137. doi: 10.1001/archsurg.2007.55.
- Brauckhoff M., Gimm O., Thanh P. N., Brauckhoff K., Ukkat J., Thomusch O., Dralle H. First experiences in intraoperative neurostimulation of the recurrent laryngeal nerve during thyroid surgery of children and adolescents. J Pediatr Surg. 2002. 37 (10):1414–1418.
- Гостимский А. В. Хирургическое лечение детей и подростков с патогенетически разным раком щитовидной железы // Диссертация доктора медицинских наук. 14.00.35, 14.00.14. Санкт-Петербург, 2009. С. 207.
- Horvath E., Rossi R., Franco C., Niedmann JP., Castro A., Dominguez M. An ultrasonogram reporting system for thyroid nodules stratifying cancer risk for clinical management. J Clin Endocrinol Metab. 2009. 94 (5): p. 1748–51. doi: 10.1210/jc.2008–1724.
- Kwak J. Y., Yoon J. H., Moon H. J., Son E. J., Park S. H., Jung H. K., Choi J. S., Kim B. M., Kim E. K. Thyroid Imaging Reporting and Data System for US Features of Nodules: A Step in Establishing Better Stratifi cation of Cancer Risk. Radiology. 2011. 260 (3): p. 892–899. doi: 10.1148/radiol.11110206.
- Franklin N. Tessler, Edward G. Grant, Jenny K. Hoang, Lincoln L. Berland, Sharlene A. Teefey, John J. Cronan and Michael D. Beland, Mary C. Frates, Lynwood W. Hammers, Ulrike M. Hamper, Jill E. Langer, Carl C. Reading, Leslie M. Scoutt, A. Thomas Stavros. ACR Thyroid Imaging. Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee. J Am Coll Radiol. 2017. 14 (5): p. 587–595. doi: 10.1016/j.jacr.2017.01.046.
- Tredici P., Gibelli B., Massaro M. A., Arrigoni C., Tradati N. Identification of patients at high risk for hypocalcemia after total thyroidectomy. Acta Otorhinolaryngol. 2011. 31: p. 144–148.
- Dionigi G., Kim H. Y., Rausei S,. Boni L., Chiang F. Y. Severity of Recurrent Laryngeal Nerve Injuries in Thyroid Surgery. World J Surg. 2016. 40 (6): p. 1373–1381. doi: 10.1007/s00268‑016‑3415‑3.
- Рычкова С. В. Качество жизни детей школьного возраста и его возрастно-гендерные особенности (по данным CHQ-87 и SF-36) // Вестник Волгоградского государственного медицинского университета. 2009. 2: p. 69–71.
- Kabaker A. S., Nikiforov Y. E., Armstrong M. J., Hodak S. P., Stang M. T., McCoy K. L., Carty S. E., Yip L. Suspicious ultrasound characteristics predict BRAF V600E-positive papillary thyroid carcinoma. Thyroid. 2012. 22 (6): p. 585–589. doi: 10.1089/thy.2011.0274.