ATYPICAL MANIFESTATION OF THE PROPOFOL INFUSION SYNDROME IN A 6-MONTH-OLD CHILD

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Abstract

The authors present the case of the propofol infusion syndrome (PrIS) in a 6-month-old. The first symptoms were represented by the unexplained central nervous system disturbances such as sopor that remained during 3 days after the agent was discontinued.

About the authors

V. V. Lazarev

Pirogov Russian National Research Medical University

Author for correspondence.
Email: 1dca@mail.ru

Dr.Sci (med), professor, Chairman of the Department of Pediatric Anesthesiology and Intensive Care,

Moscow

Россия

A. A. Bystrova

Russian Children’s Clinical Hospital

Email: 1dca@mail.ru

Reanimatologist of pediatric intensive care unit,

Moscow

Россия

G. P. Bryusov

Russian Children’s Clinical Hospital

Email: 1dca@mail.ru

Chairman of pediatric intensive care unit,

Moscow

Россия

L. E. Tsypin

Pirogov Russian National Research Medical University

Email: 1dca@mail.ru

Dr.Sci (med), professor, Professor of the Department of Pediatric Anesthesiology and Intensive Care,

Moscow

Россия

T. G. Popova

Pirogov Russian National Research Medical University

Email: 1dca@mail.ru

Cand. Sci. (Med.), Associate Professor of the Department of Pediatric Anesthesiology and Intensive Care,

Moscow

Россия

References

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  3. Parke T. J. et al. Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports. BMJ. 1992;305: 613–616.
  4. Fong J. J., Sylvia L., Ruthazer R. Predictors of mortality in patients with suspected propofol infusion syndrome. Crit Care Med. 2008.36(8):2281–7.
  5. Romero P. C., Morales R. M., Donaire R. L. et al. Severe lactic acidosis caused by propofol infusion: report of one case. Rev Med Chil. 2008. 36(1):88–92.
  6. Fodale V., La Monaca E. Propofol infusion syndrome: an overview of a perplexing disease. Drug Saf. 2008.31(4):293–303.
  7. Playfor S. D., Venkatesh K. Current patterns of propofol use in PICU in the United Kingdom and North America. Paediatr Anaesth. 2004.14(6):501–4.
  8. Kruessell M. A. Use of propofol in pediatric intensive care units: a national survey in Germany. Pediatr Crit Care Med. 2012.13(3):150–4.
  9. Rosenfeld-Yehoshua N. Propofol Use in Israeli PICUs. Pediatr Crit Care Med. 2016.17(3):117–20.

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Copyright (c) 2018 Lazarev V.V., Bystrova A.A., Bryusov G.P., Tsypin L.E., Popova T.G.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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