ALTERATIONS INTESTINAL MICROFLORA IN CHILDREN WITH ACUTE CATARRHAL APPENDICITIS

The article deals with the effect of altered biocenosis of the cecum on the development of acute appendicitis in children and simulation of acute appendicitis of local dysbiosis in the cecum and intestinal infection. To this end, investigations of microflora in the cecum and the rectum in 96 children who were operated for acute catarrhal appendicitis (ACA) and 42 children (control group) hospitalized with injuries, fractures and wounds of ileocecal angle. Of the 96 children, diagnosis of acute catarrhal appendicitis was histologically confirmed in 58. In 41 children the diagnosis was not confirmed. A decreased bifidobacteria count was revealed in 95% of children. In control group, bifidobacteria count in ileocecal angle of the cecum was 10⁹-10¹² and fecal bifidobacteria count was 10⁷-10¹⁰. Also, pathogenic and conditionally pathogenic bacteria were detected in the cecum of children with unconfirmed diagnosis of acute catarrhal appendicitis, i. e. they simulated acute appendicitis. Fecal bacteria count was lower than that in the cecum. The children with confirmed ACA showed the presence of conditionally pathogenic bacteria.

острый аппендицит, слепая кишка, микрофлора, биоценоз, подтвержденный, неподтвержденный, кишечная инфекция, содержание, снижение, увеличение, acute appendicitis, cecum, microflora, biocenosis, confirmed, unconfirmed, intestinal infection, content, reduction, increase