MODERN VIEW ON THE DEVELOPMENT AND TREATMENT OF HYPOSPADIA

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Abstract

Hypospadia is a malformation of the penis when incomplete fusion of ureteral folds and the ectopy of the ureteral outlet are observed; depending on its position according to Barcat there are anterior, medium and posterior forms of hypospadias. The main reasons for hypospadias development are genetic disturbances and hormonal shifts such as a low level of testosterone. Peculiarities of the prepuce skin blood supply in hypospadias are irregular and diffuse type of vascular branching and insufficient prepuce skin vascularization pointing at the conjugation of penis malformation disturbances and dysangiogenesis. The degree of vascularization of prepuce skin derma various in three forms of hypospadia also produces a significant effect on the favourable course of the postoperative period. Both its excessive and weak blood supply can complicate the course of the postoperative period forming ureteral fistulas. An inflammatory component stimulating the pathological angiogenesis is considered as the aggravating factor. Sufficient blood supply of the prepuce skin in the lack of a pronounced inflammatory reaction is an important criterion of favourable outcome of the postoperative period. 

About the authors

L. O. Severgina

I. M. Sechenov First Moscow State University

Author for correspondence.
Email: fake@neicon.ru
Доктор медицинских наук, профессор кафедры патологической анатомии лечебного факультета имени академика А. И. Струкова Россия

L. B. Menovschikova

N. I. Pirogov Russian National Research Medical University of the Ministry of Health of Russia

Email: fake@neicon.ru
Доктор медицинских наук, профессор кафедры детской хирургии Россия

I. A. Korovin

I. M. Sechenov First Moscow State University

Email: fake@neicon.ru
Студент 3‑го курса лечебного факультета Россия

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Copyright (c) 2016 Severgina L.O., Menovschikova L.B., Korovin I.A.

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