PREDICTORS OF SURVIVAL IN INFANTS WITH ACUTE RENAL FAILURE

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Abstract

The purpose of our trial was to evaluate the predictors of unfavorable outcome in infants with acute renal failure (ARF) when using peritoneal dialysis (PD). Methods. Design: retrospective, observational study. We performed PD in 31 patients (aged 2 to 37 months; with the average age of 24.6+8.3 months) within 2009-2015. ARF severity was assessed following RIFLE and AKIN. Lethality, treatment duration at ICU were considered as end points. PD was performed on the 5+0.7 day from the onset of the disease and 2.1+07 days of admittance. PD duration was 13.6+5.1 days. Treatment duration at ICU was 23.2+3.1 days. Results. Three fourth of the examined children had clinical signs of systemic inflammatory response; primary site of infection almost in every patient was the intestine and they had anuria. At the moment of dialysis renal failure based on the RIFLE criteria was observed in 9 patients, renal insufficiency in 22, 2 stage under AKIN classification. Conclusions. The most significant predictors of lethal outcome in ARF treated using PD in infants are the late onset of PD (insufficiency staged based on the RIFLE criteria) HR-1.8, multiple organ failure (HP-3.1) and preservation of diuresis rate less than 0.5 ml/kg/an hour (HR-2.4).

About the authors

I. Z. Latypov

State Budgetary Healthcare Institution Republican Children’s Clinical Hospital of the Ministry of Health of the Republic of Bashkortostan

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

R. Z. Akhmetshin

State Budgetary Educational Institution of Higher Professional Education Bashkir State Medical University of the Ministry of Health of the Russian Federation

Email: noemail@neicon.ru
Russian Federation

P. I. Mironov

State Budgetary Educational Institution of Higher Professional Education Bashkir State Medical University of the Ministry of Health of the Russian Federation

Email: mironovpi@mail.ru
Russian Federation

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Copyright (c) 2016 Latypov I.Z., Akhmetshin R.Z., Mironov P.I.

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