GLUTAMINE SOLUTION IN PARENTERAL NUTRITION IN PATIENTS WITH SURGICAL PATHOLOGY

封面


如何引用文章

全文:

详细

The article presents literature review on the usage of glutamine solution in the parenteral nutrition of patients with surgical pathology (burns, trauma, cancer). It considers modern approaches to parenteral nutrition using the glutamine solution; the clinical effect is displayed. Experience of using the glutamine solution within the last thirty years in patients with different surgical diseases is shown in the article.

作者简介

Yu. Erpuleva

Children’s City Clinical Hospital № 9 named. G. N. Speransky;
The First Moscow Medical Sechenov University of the Ministry of Health of Russia

编辑信件的主要联系方式.
Email: j_stier@mail.ru

Yulia W. ERPULEVA - Dr Sсi (Med), Professor of the Department of Pediatrics and Pediatric Infectious Diseases, Faculty of Pediatrics Sechenov First Moscow State Medical University

8/2, Trubetskaya st., Moscow, 119991

俄罗斯联邦

Yu. Kucherov

Children’s City Clinical Hospital № 9 named. G. N. Speransky;
Pirogov Russian National Research Medical University

Email: ykucherov@mail.ru

Yurii I. KUCHEROV - Dr Sсi (Med), Рrofessorof Children’s Medicine Department of Pirogov Medical University

1, b.7, Ostrovityanova st., Moscow, 117997

俄罗斯联邦

S. Adleiba

Children’s City Clinical Hospital № 9 named. G. N. Speransky;
Pirogov Russian National Research Medical University

Email: saidanczd@mail.ru

Saida R. ADLEIBA - Doctor-pediatric surgeon of Surgery Unit of Speransky Children’s Municipal Clinical Hospital No. 9

29, Shmitovsky proezd,Moscow,Russia, 123317 

 

俄罗斯联邦

参考

  1. Гельфанд Б. Р., Мамонтова О. А., Белоцерковский Б. З., Шипилова Т. В. Эффективность дипептивена как компонента нутритивной терапии у больных с абдоминальным сепсисом (краткий обзор литературы и результаты собственных исследований)./ Российский государственный медицинский университет, ГКБ № 1 им. Н. И. Пирогова г. Москвы. https://www.fresenius.com/ru/documents/36_GelfandGlutamin_Manual.pdf.
  2. Джозеф Ней. Отдел педиатрии и неонатологии университета Флориды, Гейневилль, США. Journal of Nutrition. 2001;131 (supplement): 2585–9.
  3. Лейси Дж. М.., Кроуч Дж. Б., Бенфелл К. Эффекты парентерального питания с добавкой глутамина у недоношенных детей. Journal of Nutrition, 2001; 131 (Supplement): 2585–9.
  4. Лекманов А. У., Ерпулева Ю. В., Золкина И. В. Эффективность использования раствора глютамина у детей с тяжелой ожоговой и сочетанной травмой в отделении интенсивной терапии.// Вестник интенсивной терапии – 2013. – № 1. – с. 49–51.
  5. Ложкин С. Н., Тиканадзе А. Д., Тюрюмина М. И. Глутамин и его роль в интенсивной терапии. //Вестник интенсивной терапии – 2003. – № 4. – с. 34–55.
  6. Цветков Д. С. Влияние глутамина на функциональное состояние кишечника у больных в критическом состоянии.// Российский онкологический научный центр им Н. Н. Блохина, РАМН, Москва, Общая реаниматология – 2009. – с. 74–80.
  7. Babst R., Horig H., Stehle P. Glutamine peptide supplemented long-term total parenteral nutrition: effects on intracellular and extracellular amino acid patterns, nitrogen economy, and tissue morphology in growing rats. JPEN J. Parenter Enteral Nutr. 1993; 17: 566–74. PMID: 8003104
  8. Bober-Olesiska K., Kornacka M. K. Effects of glutamine supplemented parenteral nutrition on the incidence of necrotizing enterocolitis, nosocomial sepsis and length of hospital stay in very low birth weight infants. Med. Wieku. Rozwoj. – 2005; 9 (3): Pt.1:325–33 PMID: 16547380
  9. Calder P. C. Glutamine and the immune system. Institute of Human Nutrition, University of Southampton, Bassett Crescent East, Southampton and Hugh Sinclair Unit of Human Nutrition, Department of Food Science and Technology, University of Reading, Whiteknights, Reading, United Kingdom 1999;227–41. DOI https://doi.org/10.1007/BF01366922.
  10. Ding L. A., Li J. S. Effects of glutamine on intestinal permeability and bacterial translocation in TPN-rats with endotoxemia. World J. Gastroenterol. 2003; 9 (6): 1327–32 doi: 10.3748/wjg.v9.i6.1327
  11. Fish J., Sporay G., Beyer K. A prospective randomized study of glutamine-enriched parenteral compared with enteral feeding in postoperative patients Am J. Clin Nutr 1997; 65:977–83 PMID: 9094882
  12. Foitzik T., Stufler M., Hotz H. G. Glutamine stabilizes intestinal permeability and reduces pancreatic infection in acute experimental pancreatitis. J. Gastrointest Surg. 1997; 1: 40–7. PMID: 9834329
  13. Goeters C., Wenn A., Mertes N. Parenteral L-alanyl-L-glutamine improves 6‑month outcome in critically ill patients. Crit Care Med. 2002; 30: 2032–7. doi: 10.1097/01.CCM.0000025908.95498. A3
  14. Griffits R. D., Allen K. D., Andrews F. J. Infection, multiple organ failure, and survival in the intensive care unit: Influence of glutamine-supplemented parenteral nutrition on acquired infection. Nutrition 2002; 18:546–52 PMID: 12093428
  15. Jiang Z.‑M., Cao J. D., Zhu X. G. The impact of alanyl-glutamine on clinical safety, nitrogen balance, intestinal permeability, and clinical outcome in postoperative patients: A randomized, double-blind, controlled study of 120 patients. J. Parenter Enteral Nutr 1999; 23:62–6. PMID: 10483898
  16. Klimberg V. S., Souba W. W., Salloum R. M. Intestinal glutamine metabolism after massive small bowel resection. Am J. Surg. 1990; 159: 27–33. PMID: 2294800
  17. Morlion B. J. Total parenteral nutrition with glutamine dipeptide after major abdominal surgery: a randomized, double blind, controlled study. Ann Surg 1998 Feb; 227 (2):3028. PMID: 9488531
  18. Mok E., Hankard R. Glutamine supplementation in sick children: is it beneficial? J. Nutr. Metab. 2011;61 (5): 97–148. doi: 10.1155/2011/617597
  19. Neu J. Glutamine in the fetus and critically III Low birth weight neonate: metaboLism and mechanism of action. J. Nutr. 2001;131 (9) SuppL:2585–9. doi: 10.1093/jn/131.9.2585
  20. Poindexter B. B., Ehrenkranz R. A., Stoll B. J. Parenteral glutamine supplementation does not reduce the risk of mortality or late-onset sepsis in extremely low birth weight infants. Pediatrics. 2004;113 (5):1209–15. doi: 10.1542/peds.113.5.1209
  21. Peng X., Yan H., You Z. Effects of enteral supplementation with glutamine granules on intestinal mucosal barrier function in severe burned patients. Burns 2004; 30:135–9.
  22. Rombeau J. L., Takala J. Summary of round table conference: Gut disfunction in critical illness. Intensive Care Med 1997;23:476–9. doi: 10.1007/s001340050361. PMID: 9142592
  23. Rombeau J. L. A review of the effects of glutamine-enriched diets on experimentally induced enterocolitis. JPEN J. Parenter Enteral Nutr. 1990; 14: 100–5. PMID: 2119454
  24. Souba, W. W. Inlerorgan ammonia metabolism in health and disease: a surgeon’s view. J. P. E. N. 1987;11:569 PMID: 3323556
  25. Swank G. M., Deitch E. A. Role of the gut in multiple organ failure: Bacterial translocation and permeability changes. World J. Surg 1996; 20:411–7. PMID: 8662128
  26. Tamada H., Nezu R., Matsuo Y. Alanyl glutamine-enriched total parenteral nutrition restores intestinal adaptation after either proximal or distal massive resection in rats. JPEN J. Parenter Enteral Nutr. 1993; 17: 236–42.doi. org/10.1177/0148607193017003236
  27. Thompson S. W., McClure B. G., Tubman T. R. A randomized, controlled trial of parenteral glutamine in ill, very low birthweight neonates. J. Pediatr. Gastroenterol. Nutr. 2003; 37 (5):550–3. PMID: 14581795
  28. Yoshida S., Yunoki T., Aoyagi K., Ohta J., Ishibashi N., Noake T., Kakegawa T. Effect of glutamine supplement and hepatectomy on DNA and protein synthesis in the remnant liver. J. Surg. Res. 1995;59:475, PMID: 7564320

补充文件

附件文件
动作
1. JATS XML

版权所有 © Erpuleva Y.W., Kucherov Y.I., Adleiba S.R., 2018

Creative Commons License
此作品已接受知识共享署名-非商业性使用-禁止演绎 4.0国际许可协议的许可。

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: ПИ № ФС 77 - 81892 от 24.09.2021 г.


##common.cookie##