THE MORPHOLOGICAL CHARACTERISTICS OF THE BIOPSY IN CHILDREN WITH SPINAL DYSRAPHISM

Biopsies of removed spina bifida and regional tissue in 21 children (before the age of 1 year) who were operated on meningoradiculocele and 18 biopsies in combination with congenital intradural malformations were exposed to morphological study. Retrospective analysis of histological features of the various forms of spina bifida identified an objective assessment of expediency of different methods of surgical treatment according to the form of malformation. The results showed that skin covering the area of all forms of spina bifida is characterized by distinct polymorphism. At the same time the specific changes of epidermis were not found in the various forms of spina bifida. The often result of operations, which were conducted outside of a specialized agency, is aggravation of the disintegration and demyelization processes caused by secondary arachnoid, soft and dura mater adhesions, greater involvement of the spinal cord pathways and roots in the adhesions, severe disorders of local hemodynamics.

спинно-мозговая грыжа, демиелинизация, биопсия, спинальные тканевые мальформации, spina bifida, demyelization, biopsy, spinal tissue malformations