SHORT BOWEL SYNDROME IN CHILDREN

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Abstract

Short bowel syndrome (SBS) continue to be important clinical problem in pediatric population due to high mortality and morbidity rates, as well as their devastating socioeconomic effects. In this paper, the etiology of SBS, its pathophysiology, the cellular and molecular mechanisms of intestinal adaptation, are reviewed. The most common complications of SBS are outlined with strategies to reduce them. The medical management and nutritional support of a patient with SBS is complex and requires a multidisciplinary. A review of the pharmacologic agents and growth factors that have been studied experimentally and administered clinically for the management of short bowel syndrome is presented.
Surgical procedures to promote intestinal adaptation and intestinal lengthening have largely changed the available options for non-transplant interventions.

About the authors

I. G. Sukhotnik

The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Dept of Pediatric Surgery, Bnai Zion Medical Center

Author for correspondence.
Email: igor-dr@internet-zahav.net
Профессор Израильского Института Технологии, Медицинский Факультет имени Руфи и Брюса Раппопорт, Кафедра детской хирургии, Медицинский Центр Бней-Цион, Хайфа, Израиль. Dept Pediatric Surgery B, BnaiZionMedicalCenter 47 Golomb St., P.O.B. 4940, Haifa, 31048, Israel. Ph (h): 972-4-8256815, Ph (b): 972-4-8359647, Fax-972-4-8359620. Israel

References

  1. Vanderhoof J.A. Short bowel syndrome. Neonat Gastroenterol 1996;23:377–386.
  2. Booth I.W., Lander A.D. Short bowel syndrome. Bailliere’s Clin Gastroenterol 1998;12:739–772.
  3. Sigalet D.L. Short bowel syndrome in infants and children: an overview. Semin. Pediatr. Surg. 2001;10:49–55.
  4. Coran A.G., Spivak D., Teitelbaum D.H. An analysis of the morbidity and mortality of short-bowel syndrome in the pediatric age group. Eur. J. Pediatr. Surg. 1999; 9:228–230.
  5. Georgeson K.E., Breaux C.W. Outcome and intestinal adaptation in neonatal short bowel syndrome. J. Pediatr. Surg. 1992; 27:344–350.
  6. Galea M. H., Holliday H., Carachi R., Kapila L. Short-bowel syndrome: a collective review. J. Pediatr. Surg, 27: 592–596, 1992.
  7. Rickham P.P., Irving I., Shmerling D.H. Long-term results following extensive small bowel resection in the neonatal period. Prog. Pediatr. Surg. 1977; 10: 65–75.
  8. Klish W.J., Putnam T.C. The short gut. Am. J. Dis. Child, 1981; 135:1056–1061.
  9. Urban E., Weser E. (1980) Intestinal adaptation to bowel resection, In Stollerman GH (ed): Advances in internal medicine, vol 26. Chicago, Year Book Medical Publishers, Inc, 1980; pp 265–291.
  10. Crenn P., Coudray-Lucas C., Thuillier F., Cynober L., Messing B. Postabsorptive plasma citrulline concentration is a marker of absorptive enterocyte mass and intestinal failure in humans. Gastroenterology 2000; 119:1496–1505.
  11. Potts W.J. Pediatric surgery. J. Am. Med. Assoc. 1955; 157: 627–630.
  12. Pilling G.P., Cresson S.L. Massive resection of small intestine in the neonatal period. Report of two successful cases and review of the literature. Pediatrics 1957; 19: 940–948.
  13. Wilmore D.W. Factors correlating with a successful outcome following extensive intestinal resection in the newborn infant. J. Pediatr. 1972; 80: 88–93.
  14. Wilmore D.W., Groff D.B., Bishop H.C., Dudrick S.J. Total parenteral nutrition in infants with catastrophic gastrointestinal anomalies. J. Pediatr. Surg. 1969; 4: 181–189.
  15. Dorney S.F., Ament M.E., Berquist W.E., Vargas J.H., Hassall E. Improved survival in very short small bowel of infancy with use of long-term parenteral nutrition. J. Pediatr. 1985;107:521–525.
  16. Reyes J. Intestinal transplantation for children with short bowel syndrome. Sem. Pediatr. Surg. 2001; 10:99–104.
  17. Chaet M.S., Farrell M.K., Ziegler M.M., Warner B.W. Intensive nutritional support and remedial surgical intervention for extreme short bowel syndrome. Pediatr. Gastroenterol. Nutr. 1994;19:295–298.
  18. Goulet O., Baglin-Gobet S., Jais J.P., Michel J.L., Jan D., Ricour C. Outcome and long-term growth after extensive small
  19. bowel resection in the neonatal period: a survey of 87 children. Eur. J. Pediatr. Surg. 2005;15:95–101.
  20. Salihu H.M., Aliyu Z.Y., Pierre-Louis B.J., Obuseh F.A., Druschel C.M., Kirby R.S. Omphalocele and gastroschisis: black-white disparity in infant survival. Birth Defects Res. A Clin. Mol. Teratol. 2004; 70:586–591.
  21. Hackam D.J., Reblock K.K., Redlinger R.E., Barksdale E.M. Diagnosis and outcome of Hirschsprung’s disease: does age really matter? Pediatr. Surg. Int. 2004;20:319–322.
  22. Cain W.S., Howel C.G., Ziegler M.M. Rectosigmoid perforation and intestinal evisceration from transanal suction. J. Pediatr. Surg. 1983; 18:10–13.
  23. DiBaise J.K., Young R.J., Vanderhoof J.A. Intestinal rehabilitation and the short bowel syndrome. Am. J. Gastroenterol. 2004; 99:1386–1395.
  24. Sturm A., Layer P., Goebell H. Short-bowel syndrome: an update on the therapeutic approach. Scand. J. Gastroenterol. 1997; 32:289–296.
  25. Thompson J.S. Inflammatory disease and outcome of short bowel syndrome. Am. J. Surg. 2000; 180:551–555.
  26. Buchman A.L. The Medical and surgical management of short bowel syndrome. Med. Gen. Med. Gastroenterology 2004; 6: 1–2.
  27. Howard L., Ament M., Fleming C.R., Shike M., Steiger E. Current use and clinical outcome of home parenteral and enteral nutrition therapies in the Unated States. Gastroenterology, 1995; 109: 355–365.
  28. Howard L., Ament M., Fleming C.R. Four years of North American registry home parenteral nutrition outcome data and their implications for patient management. JPEN 1991; 15:384–393.
  29. Grant D. Intestinal transplantation: 1197 report of the international registry. Transplantation 1999; 67: 1061–1064.
  30. Abu-Elmagd K., Reyes J. Factors impacting the survival of children with intestinal failure referred for intestinal transplantation. J. Pediatr. Surg. 1999; 34:27–32.
  31. Chungfat N., Dixler I., Cohran V., Buchman A., Abecassis M., Fryer J. Impact of parenteral nutrition-associated liver disease on intestinal transplant waitlist dynamics. J. Am. Coll. Surg. 2007;205:755–761.
  32. Schalamon J., Mayr J., Hollwarth M. Mortality and economics in short bowel syndrome. Best Pract. Res. Clin. Gastroenterol. 2003;17:931–942.
  33. Puntis J.W. The economics of home parenteral nutrition. Nutrition 1998;14:809–812.
  34. Spencer A., Kovacevich D., McKinney-Barnett M., Hair D., Canham J., Maksym C., Teitelbaum D.H. Pediatric shortbowel syndrome: the cost of comprehensive care. Am. J. Cluin. Nutr. 2008; 88: 1552–1559.
  35. Goulet O., Sauvat F., Ruemmele F., Caldari D., Damotte D., Cezard J.P., Lacaille F., Canioni D., Hugot J.P., Berebi D., Sarnacki S., Colomb V., Jan D., Aigrain Y., Revillon Y. Results of the Paris program: ten years of pediatric intestinal transplantation. Transplant. Proc. 2005; 37:1667–1670.
  36. Touloukian R.J., Smith G.J.W. Normal intestinal length in preterm infants. J. Pediatr. Surg. 1983; 18: 720–723.
  37. Shatari T., Clark M.A., Lee J.R., Keighley M.R. Reliability of radiographic measurement of small intestinal length. Colorectal. Dis. 2004; 6:327–329.
  38. Summers R.W., Kent T.H., Osborne J.W. Effects of drugs, ileal obstruction and irradiation on rat gastrointestinal propulsion. Gastroenterology, 1970; 59:731–739.
  39. Wright N., Alison M. The Biology of Epithelial Cell Populations. Clarendon, Oxford, 1984.
  40. Booth C., Potten C.S. Gut instincts: thoughts on intestinal epithelial stem cells. J. Clin. Invest. 2000;105:1493–1499.
  41. Goumans M.J., Mummery C. Functional analysis of the TGFb receptor/Smad pathway through gene ablation in mice. Int. J. Dev. Biol. 2000;44: 253–265.
  42. Parekh N.R., Steiger E. Short bowel syndrome. Curr. Treat Options Gastroenterol. 2007;10:10–23.
  43. Dudrick S.J., Latifi R. Management of short-bowel syndrome. In: Kirby DF, Dudrick SJ, eds. Practical handbook of nutrition in clinical practice. Boca Raton: CRC Press, 1994.
  44. Beyer P.L., Flynn M.A. Effect of high- and low-fiber diets on human feces. J. Am. Diet. Assoc. 1978; 72:271–272.
  45. Vanderhoof J.A., Langnas A.N. Short bowel syndrome in children and adults. Gastroenterology 113: 1767–1778, 1997.
  46. Hylander E., Ladefoged K., Jarnum S. Nitrogen absorption following small intestinal resection. Scand. J. Gastroenterol. 1980;15:853–858.
  47. Woolf G.M., Miller C., Kurian R., Jeejeebhoy K.N. Nutritional absorption in short bowel syndrome: evaluation of fluid, calorie, and divalent cation requirements. Dig. Dis. Sci. 1987;32:8–15.
  48. Vanderhoof J.A., Burkley K.T., Antonson K.T. Potential for mucosal adaptation following massive small bowel resection in 3‑week-old versus 8‑week-old rats. J. Pediatr. Gastroenterol. Nutr. 1983;2:672–676.
  49. Chiba T., Ohi R. Do we still need to collect stool? Evaluation of visualized fatty acid absorption: experimental studies using rats. J. Parenter. Enteral. Nutr. 1998; 22:22–26.
  50. Molina M.T., Ruiz-Cutierrez V., Vazquez C.M. Changes in uptake of linoleic acid and cholesterol by jejunal sacs of rats in vitro, after distal small bowel resection. Scand. J. Gastroenterol. 1990; 25:613–621.
  51. Tilson M.D., Boyer J.L., Wright H.K. Jejunal absorption of bile salts after resection of the ileum. Surgery 1975;77:231–234.
  52. Pitchumoni C.S. Pancreas in primary malnutrition disorders. Am. J. Clin. Nutr. 1973; 26:374–379.
  53. Biller J.A. (1987) Short bowel syndrome. In: Grand RI, Sutphen JL, Dietz WH (eds) Pediatric nutrition. Theory and practice. Butterworth, Stoneham, MA, pp 481–487.
  54. Haymond H.E. Massive resection of the small intestine: analysis of 257 collected cases. Surg. Gynecol. Obstet. 1953;61:693–705.
  55. Ladefoged K., Nicolaidou P., Jarnum S. Calcium, phosphorus,magnesium, zinc and nitrogen balance in patients with severe short bowel syndrome. Am. J. Clin. Nutr. 1980;33:2137–2144.
  56. Wolman S.L., Anderson G.H., Marliss E.B., Jeejeebhoy K.N. Zinc in total parenteral nutrition: requirements and metabolic effects. Gastroenterology 1979;76:458–467.
  57. Ruppin H., Bar-Meir S., Soergel K.H., Wood C.M., Schmitt M.G. Jr. Absorption of short-chain fatty acids by the colon. Gastroenterology 1980; 78:1500–1507.
  58. Mitchel J.E., Breuer K.I., Zuckerman L., Berlin J., Schilli L., Dunn J.K. The colon influences ileal resection diarrhea. Dig. Dis. Sci. 1980; 25:33–41.
  59. Johnson C.P., Sarna S.K., Zhu Y.R., Buchmann E., Bonham L., Telford G.L., Roza A.M., Adams M.B. Delayed gastroduodenal emptying is an important mechanism for control of intestinal transit in short gut syndrome. Am. J. Surg. 1996; 171:90–95.
  60. Nightingale J.M., Kamm M.A., van der Sijp J.R., Ghatei M.A., Bloom S.R., Lennard-Jones J.E. Gastrointestinal hormones in short bowel syndrome. Peptide YY may be the ‘colonic brake’ to gastric emptying. Gut 1996; 39:267–272.
  61. Purdum P.P., Kirby D.F. Short bowel syndrome: a review of the role of nutrition support. JPEN J. Parenter Enteral. Nutr. 1991; 15:93–101.
  62. Hyman P.E., Everett S.L., Harada T. Gastric acid hypersecretion in short bowel syndrome in infants: association with extent of resection and enteral feeding. J. Pediatr. Gastroenterol. Nutr. 1986;5:191–197.
  63. Wright J.K. Short gut syndrome- options for management. Compr. Ther. 1992; 18:5–8.
  64. Stringer M.D., Puntis J.W.L. Short bowel syndrome. Arch. Dis. Child 1995; 73:170–173.
  65. Dudrick S.J., Latifi R. Management of short-bowel syndrome. In: Kirby DF, Dudrick SJ, eds. Practical handbook of nutrition in clinical practice. Boca Raton: CRC Press, 1994.
  66. Pakarinen M.P., Koivusalo A.I., Rintala R.J. Outcomes of intestinal failure- a comparison between children with short bowel and dysmotile intestine. J. Pediatr. Surg. 2009;44:2139–2144.
  67. Bueno J., Guiterrez J., Mazariegos G.V., Abu-Elmagd K., Madariaga J., Ohwada S., Kocoshis S., Reyes J. Analysis of patients with longitudinal intestinal lengthening procedure referred for intestinal transplantation. J. Pediatr. Surg. 2001;36:178–183.
  68. Ziegler M.M. Short bowel syndrome: remedial features that influence outcome and the duration of parenteral nutrition. J. Pediatr. 1997;131: 335–336.
  69. Teitelbaum D.H. Parenteral nutrition-associated cholestasis. Curr. Opin. Pediatr. 1997;9:270–275.
  70. Spencer A.U., Neaga A., West B., Safran J., Brown P., Btaiche I., Kuzma-O’Reilly B., Teitelbaum D.H. Pediatric short bowel syndrome: redefining predictors of success. Ann. Surg. 2005;242:403–409.
  71. Sigalet D., Boctor D., Robertson M., Lam V., Brindle M., Sarkhosh K., Driedger L., Sajedi M. Improved outcomes in paediatric intestinal failure with aggressive prevention of liver disease. Eur. J. Pediatr. Surg. 2009;19:348–353.
  72. Martínez M., Fabeiro M., Dalieri M., Barcellandi P., Prozzi M., Hernández J., Alberti M., Fernández A. Outcome and survival of pediatric Short Bowel Syndrome (SBS). Nutr. Hosp. 2011;26:239–242.
  73. Rowe M.I., O’Neill J.A., Grosfeld J.L., Fonkalsrud, Coran A.G. (1995) Short-bowel syndrome. In Rowe MI, O’Neill JA, Grosfeld JL, Fonkalsrud, Coran AG (eds) Essentials of Pediatric Surgery. Mosby-Year book, pp 536–541,
  74. Greenberg R.G., Moran C., Ulshen M., Smith P.B., Benjamin D.K. Jr, Cohen-Wolkowiez M. Outcomes of catheterassociated infections in pediatric patients with short bowel syndrome. J. Pediatr. Gastroenterol. Nutr. 2010; 50:460–462.
  75. Cole C.R., Frem J.C., Schmotzer B., Gewirtz A.T., Meddings J.B., Gold B.D., Ziegler T.R. The rate of bloodstream infection is high in infants with short bowel syndrome: relationship with small bowel bacterial overgrowth, enteral feeding, and inflammatory and immune responses. J. Pediatr. 2010; 156:941–947.
  76. Duran B. The effects of long-term total parenteral nutrition on gut mucosal immunity in children with short bowel syndrome: a systematic review. BMC Nurs. 2005; 4: 1–2.
  77. O’Brien D.P., Nelson L.A., Kemp C.J., Williams J.L., Wang Q., Erwin C.R., Hasselgren P.O., Warner B.W. Intestinal permeability and bacterial translocation are uncoupled after small bowel resection. J. Pediatr. Surg. 2002; 37: 390–394.
  78. Bayes B.J., Hamilon J.R. Blind loop syndrome in children. Arch. Dis. Childhood. 1969; 44: 76–81.
  79. Kaufman S.S., Loseke C.A., Lupo J.V., Young R.J., Murray N.D., Pinch L.W., Vanderhoof J.A. Influence of bacterial overgrowth and intestinal inflammation on duration of parenteral nutrition in children with short bowel syndrome. J. Pediatr. 1997;131:356–361.
  80. Fich A., Steadman C.J., Phillips S.F., Camilleri M., Brown M.L., Haddad A.C., Thomforde G.M. Ileocolonic transit does not change after right hemicolectomy. Gastroenterology 1992;103:794–799.
  81. Riordan S.M., McIver C.J., Wakefield D., Bolin T.D., Duncombe V.M., Thomas M.C. Small intestinal bacterial overgrowth in the symptomatic elderly. Am. J. Gastroenterol. 1997;92:47–51.
  82. Dibaise J.K., Young R.J., Vanderhoof J.A. Enteric microbial flora, bacterial overgrowth, and short-bowel syndrome. Clin. Gastroenterol. Hepatol. 2006;4:11–20.
  83. Kelly D.A. Intestinal failure-associated liver disease: what do we know today? Gastroenterology 2006; 130 (2 Suppl 1): S70–77.
  84. Spencer A.U., Neaga A., West B., Safran J., Teitelbaum D.H. Pediatric short bowel syndrome redefining predictors of success. Ann. Surg. 2005; 242:403–412.
  85. Kelly D.A. Liver complications of pediatric parenteral nutrition – epidemiology. Nutrition, 1998; 14:153–157.
  86. Ng P.C., Lee C.H., Wong S.P., Lam H.S., Liu F.Y., So K.W., Lee C.Y., Fok T.F. High dose oral erythromycin decreased the incidence of parenteral nutrition-associated cholestasis in preterm infants. Gastroenterology 2007; 132:1726–1739.
  87. Schneider S.M., Joly F., Gehrardt M-F. Taurine status and response to intravenous taurine supplementation in adults undergoing long term parenteral nutrition: a pilot study. Brit. J. Nutr. 2006; 96:365–370.
  88. Muiesan P., Dhawan A., Novelli M., Mieli-Vergani G., Rela M., Heaton N.D. Isolated liver transplant and sequential small bowel transplantation for intestinal failure and related liver disease in children. Transplantation 2000; 69:2323–2326.
  89. Goulet O., Joly F., Corriol O., Colomb-Jung V. Some new insights in intestinal failure-associated liver disease. Curr. Opin. Organ. Transplant. 2009; 14:256–261.
  90. Diamond I.R., Sterescu A., Pencharz P.B., Kim J.H., Wales P.W. Changing the paradigm: omegaven for the treatment of liver failure in pediatric short bowel syndrome. J. Pediatr. Gastroenterol. Nutr, 2009; 48: 209–215.
  91. Meehan J.J., Georgeson K.E. Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome. J. Pediatr. Surg. 1997; 32:473–475.
  92. Thatch K.A., Schwartz M.Z., Yoo E.Y. Modulation of the inflammatory response and apoptosis using epidermal growth factor and hepatocyte growth factor in a liver injury model: a potential approach to the management and treatment of cholestatic liver disease. J. Pediatr. Surg. 2008; 43: 2169–2173.
  93. Lawrence J.P., Dunn S.P., Billmire D.F., Falkenstein K., Vinocur C.D., Weintraub W.H. Isolated liver transplantation for liver failure in patients with short bowel syndrome. J. Ped. Surg. 1994; 29: 751–753.
  94. Jean F. Botha, Clarivet Torres, Angie K. Iverson, Debra L. Sudan, Byers W. Shaw Jr., Alan N. Langnas. Isolated liver transplantation in infants with end-stage liver disease due to short bowel syndrome. Liver Transpl. 2006; 12;1062–1066.
  95. Hove H., Mortensen P.B. Colonic lactate metabolism and D-lactic acidosis. Dig. Dis. Sci. 1995;40:320–330.
  96. Bongaerts G., Bakkeren J., Severijnen R., Sperl W., Willems H., Naber T., Wevers R., van Meurs A., Tolboom J. Lactobacilli and acidosis in children with short small bowel. J. Pediatr. Gastroenterol. Nutr. 2000;30:288–293.
  97. Nightingale J.M.D., Lennard-Jones J.E., Gertner D.J. Colonic preservation reduces need for parenteral therapy, increases incidence of renal stones but does not change high prevalence of gall stones in patients with short bowel. Gut 1992; 33:1493–1497.
  98. Scolapio J.S., Fleming C.R. Short-bowel syndrome. Gastroenterol. Clin. North Am. 1998; 27:467–79.
  99. Nightingale J.M. Hepatobiliary, renal and bone complications of intestinal failure. Best Pract. Res. Clin. Gastroenterol. 2003;17:907–929.
  100. Berger D.L., Malt R.A. Management of the short gut syndrome. Adv. Surg. 1996; 29:43–57.
  101. Ziegler M.M. Short bowel syndrome: remedial features that influence outcome and the duration of parenteral nutrition. J. Pediatr. 1997; 131:335–336.
  102. Scolapio J.S. Effect of growth hormone and glutamine on the short bowel: five years later [review]. Gut 2000; 47:164.
  103. Berger D.L., Malt R.A. Management of the short gut syndrome. Adv. Surg. 1996; 29:43–57.
  104. Stollman N.H., Neustater B.R., Rogers A.I. Short bowel syndrome. Gastroenterologist 1996; 4:118–128.
  105. Salvino R., Ghanta R., Seidner D.L., Mascha E., Xu Y., Steiger E. Liver failure is common in adults receiving long-term parenteral nutrition. JPEN J. Parenter. Enteral. Nutr. 2006; 30:202–208.
  106. Buchman A.L. Complications of long-term home total parenteral nutrition: their identification, prevention and treatment. Dig. Dis. Sci. 2001;46:1–18.
  107. Scolapio J.S. Effect of growth hormone, glutamine, and diet on adaptation in short-bowel syndrome: a randomized, controlled study. Gastroenterology 1997; 113:1074–81.
  108. Skipper A. Dietitian’s handbook of enteral and parenteral nutrition. Rockville, MD: Aspen, 1989.
  109. Stump ES. Nutrition and diagnosis-related care, 3rd ed. Philadelphia: Lea and Febiger, 1992.
  110. Levy E., Frileux P., Sandrucci S., Ollivier J.M., Masini J.P., Cosnes J., Hannoun L., Parc R. Continuous enteral nutrition during the early adaptive stage of the short bowel syndrome. Br. J. Surg. 1988;75 (6):549–553.
  111. Scolapio J.S., Fleming C.R. Short-bowel syndrome. Gastroenterol. Clin. North Am. 1998; 27:467–79.
  112. Anderson H., Isaksson B., Sjogren B. Fat-reduced diet in the symptomatic treatment of small bowel disease. Gut 1997; 15:351–9.
  113. Stringer M.D., Puntis J.W.L. Short bowel syndrome. Arch. Dis. Child 1995; 73:170–3.
  114. Woolf G.M., Miller C., Kurian R., Jeejeebhoy K.N. Diet for patients with a short bowel: high fat or high carbohydrate? Gastroenterology 1983; 84:823–8.
  115. Woolf G.M., Miller C., Kurian R., Jeejeebhoy K.N. Nutritional absorption in short bowel syndrome: evaluation of fluid, calories, and divalent cation requirements. Dig. Dis. Sci. 1987; 32:8–15.
  116. Sundaram A., Koutkia P., Apovian C. Nutritional Management of Short Bowel Syndrome in Adults. Journal of Clinical Gastroenterology Issue: Volume 34 (3), March 2002, pp 207–220.
  117. Fleming R., George L., Stoner G.L. The importance of urinary magnesium values in patients with gut failure. Mayo Clinic Proc. 1996; 71:21–4.
  118. Klein S., Jeejeebhoy K.N. Long-term nutritional management of patients with maldigestion and malabsorption in gastrointestinal disease, 5th ed. Sleisenger M, Fordtran J, eds. Philadelphia: WB Saunders, 1993.
  119. Lennard-Jones J.E. Practical management of the short bowel. Aliment Pharmacol Ther 1994; 8:563–77.
  120. Ladefoged K, Olgaard K. Sodium homeostasis after small-bowel resection. Scand. J. Gastroenterol. 1985; 20:361–9.
  121. Allard J.P., Jeejeebhoy K.N. Nutritional support and therapy in the short bowel syndrome. Gastroenterol. Clin. North Am. 1989; 18:589–601.
  122. Wilmore D.W. Growth factors and nutrients in the short bowel syndrome. JPEN J. Parent. Enteral. Nutr. 1999;23 (5 Suppl):S117–120.
  123. Byrne T.A., Persinger R.L., Young L.S., Ziegler T.R., Wilmore D.W. New treatment of patients with short bowel syndrome: growth hormone, glutamine, and a modified diet. Ann. Surg. 1995; 222:243–255.
  124. Thompson J.S. Management of the short bowel syndrome. Gastroenterol. Clin. North Am. 1994; 23:403–420.
  125. Berger D.L., Malt R.A. Management of the short gut syndrome. Adv. Surg. 1996; 29:43–57.
  126. Purdum P.P., Kirby D.F. Short bowel syndrome: a review of the role of nutrition support. JPEN J. Parenter. Enteral. Nutr. 1991; 15:93–101.
  127. Yang H., Teitelbaum D.H. Novel Agents in the Treatment of Intestinal Failure: Humoral Factors. Gastroenterology 2006; 130 (2 Suppl 1): S117 – S121.
  128. Sigalet D.L., Martin G.R., Butzner J.D., Buret A., Meddings J.B. A pilot study of the use of epidermal growth factor in pediatric short bowel syndrome. J. Pediatr. Surg. 2005;40:763–768.
  129. Jeppesen P.B., Hartmann B., Thulesen J., Graff J., Lohmann J., Hansen B.S., Tofteng F., Poulsen S.S., Madsen J.L., Holst J.J., Mortensen P.B. Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon. Gastroenterology 2001;120:806–815.
  130. Yazbeck R. Teduglutide, a glucagon-like peptide-2 analog for the treatment of gastrointestinal diseases, including short bowel syndrome. Curr. Opin. Mol. Ther. 2010 12:798–809.
  131. PanisY., Messing B., Rivet P., Coffin B., Hautefeuille P., Matuchansky C., Rambaud J.C., Valleur P. Segmental reversal of the small bowel as an alternative to intestinal transplantation in patients with short bowel syndrome. Ann. Surg. 1997; 225:401–407.
  132. Vernon A.H., Georgeson K.E. Surgical options for short bowel syndrome. Semin. Pediatr. Surg. 2001; 10:91–98.
  133. Georgeson K., Halpin D., Figueroa R. Sequential intestinal lengthening procedures for refractory short bowel syndrome. J. Pediatr. Surg. 1994; 29:316–321.
  134. Thompson J.A., Langas A.N., Pinch L.W. Surgical approach to short-bowel syndrome: experience in a population of 160 patients. Ann. Surg. 1995;222:600–607.
  135. Wales P.W. Surgical therapy for short bowel syndrome. Pediatr. Surg. Int. 2004; 20:647–657.
  136. Bianchi A. Intestinal loop lengthening – a technique for increasing small intestinal length. J. Pediatr. Surg. 1980; 15:145–151.
  137. Pokorny W.J., Fowler C.L. Isoperistaltic intestinal lengthening for short bowel syndrome. Surg. Gynecol. Obstet. 1991;172:39–43.
  138. Bianchi A. Experience with longitudinal intestinal lengthening and tailoring. Eur. J. Ped. Surg. 1999;9:256–259.
  139. Weber T.R. Isoperistaltic bowel lengthening for short bowel syndrome in children. Am. J. Surg. 1999;178:600–604.
  140. Kim H.B., Fauza D., Garza J. Serial transverse enteroplasty (STEP): a novel bowel lengthening procedure. J. Pediatr. Surg. 2003;38:425–429.
  141. Miyasaka E.A., Brown P.I., Teitelbaum D.H. Redilation of bowel after intestinal lengthening procedures--an indicator for poor outcome. J. Pediatr. Surg. 2011;46:145–149.
  142. Alican F., Hardy J.D., Cayirili M. et al. Intestinal transplantation: laboratory experience and a report of a clinical case. Am. J. Surg. 1971; 12:150–159.
  143. Lillehei R.C., Idezuki Y., Feemster J.A. Transplantation of stomach, intestine, and pancreas: experimental and clinical observations. Surgery 1967; 62:721–741.
  144. Grant D. Current results of intestinal transplantation. The International Intestinal Transplant Registry. Lancet 1996;347: 1801–1803.
  145. Goulet O., Sauvat F., Ruemmele F. Results of the Paris program: ten years of pediatric intestinal transplantation. Transplant. Proc. 2005. 371667–1670.1670.
  146. Goulet O., Ruemmele F. Causes and Management of Intestinal Failure in Children. Gastroenterology, 2006;130: S16 – S28.

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