Russian Journal of Pediatric Surgery, Anesthesia and Intensive CareRussian Journal of Pediatric Surgery, Anesthesia and Intensive Care2219-40612587-6554Eco-Vector8910.17816/psaic89MEASURED AND DERIVED PARAMETERS OF BLOOD GAS ANALYSIS FOR CRITICALLY ILL PATIENTS. ANION GAP ESTIMATIONTorshinV. A.vatorshin@mail.ruRussian Medical Academy of Postgraduate Education151220144410911230012017Copyright © 2014, Torshin V.A.2014Article includes short historical review concerning blood gas analysis and mainly dedicated to such derived parameter as anion gap. Meaning of parameter in different critical situations is discussed. Pictured role of parameter for diagnostics of such syndrome as D-lactacidosis.анионный промежутокD-лактацидозanion gapD-lactacidosis[Astrup P., Severinghaus J. The History of Blood Gases, Acids and Bases. - Munksgaard, 1986.][Higgins C. Clinical aspects of the anion gap. - 2009; www.acutecaretesting.org.][Lolekha P., Lolekha S. Value of the anion gap in clinical diagnosis and laboratory evaluation // Clin. Chem. 1983. Vol. 29. Р. 279-283.][Feldman M., Soni N., Dickson B. Influence of hypoalbuminemia or hyperalbuminemia on the serum anion gap // J. Clin.Lab. Med. 2005. Vol. 146. Р. 317-320.][Al-Aly Z., Valdez H., Moiz A. et al. Evaluation of serum anion gap in patients with HIV // J. Nephrology. 2007. Vol. 20. Р. 727-730.][Berkman M., Ufberg J. et al. Anion gap as a screening tool for elevated lactate in patients with increased risk of developing sepsis in the emergency department // J. Emerg. Med. 2007. Vol. 36. Р. 391-394.][Kraut J., Madias N. Serum anion gap: its uses and limitations in clinical medicine // Clin. J. Am. Soc. Nephrol. 2007. N 2. Р. 162-174.]