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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский вестник детской хирургии, анестезиологии и реаниматологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4061</issn><issn publication-format="electronic">2587-6554</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">721</article-id><article-id pub-id-type="doi">10.17816/psaic721</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Study Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Inhalation anesthesia in children in outpatient dentistry: xenon or sevoflurane?</article-title><trans-title-group xml:lang="ru"><trans-title>Ингаляционная анестезия у детей в амбулаторной стоматологии: ксенон или севофлуран?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8417-3555</contrib-id><name-alternatives><name xml:lang="en"><surname>Lazarev</surname><given-names>Vladimir V.</given-names></name><name xml:lang="ru"><surname>Лазарев</surname><given-names>Владимир Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Head of Department of pediatric anesthesiology and intensive therapy</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующий кафедрой детской анестезиологии и интенсивной терапии</p></bio><email>lazarev_vv@inbox.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2771-3134</contrib-id><name-alternatives><name xml:lang="en"><surname>Khaliullin</surname><given-names>Dinar M.</given-names></name><name xml:lang="ru"><surname>Халиуллин</surname><given-names>Динар Мансурович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>anesthesiologist resuscitator</p></bio><bio xml:lang="ru"><p>врач анестезиолог-реаниматолог</p></bio><email>dr170489@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Федеральное государственное автономное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">LC “Dental Forte Elit”</institution></aff><aff><institution xml:lang="ru">ООО «Дентал Форте Элит»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-12-29" publication-format="electronic"><day>29</day><month>12</month><year>2020</year></pub-date><volume>10</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>435</fpage><lpage>443</lpage><history><date date-type="received" iso-8601-date="2021-02-09"><day>09</day><month>02</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-03-01"><day>01</day><month>03</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Lazarev V.V., Khaliullin D.M.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, Лазарев В.В., Халиуллин Д.М.</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Lazarev V.V., Khaliullin D.M.</copyright-holder><copyright-holder xml:lang="ru">Лазарев В.В., Халиуллин Д.М.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://rps-journal.ru/jour/article/view/721">https://rps-journal.ru/jour/article/view/721</self-uri><abstract xml:lang="en"><p><bold>Abstract. </bold>The choice of optimal anesthetic in outpatient dental practice is an important stage in treatment plan preparation for children who need oral sanitation under general anesthesia. Few works were devoted to the comparative characterization of sevoflurane and xenon, especially in conditions of outpatient dental practice.</p> <p><bold>Aim</bold>. This study aimed to compare the characteristics of xenon and sevoflurane inhalation anesthesia at the stage of maintaining anesthesia in outpatient dental practice.</p> <p><bold>Materials and methods</bold>. This is an open, comparative, and randomized study, in parallel groups with random sampling. A total of 103 patients of both sexes aged 2–12 years were included. Children were divided into 2 groups: group 1 (35 children), with sevoflurane anesthesia and group 2 (68 children), with xenon anesthesia. In each and between groups at stages of anesthesia, data from the bispectral (BIS) index, heart rate, blood pressure, lung ventilation, glucose, acid-base status, and ionic composition of venous blood were monitored.</p> <p><bold>Results</bold>. Significant differences between groups were observed in the BIS-index values at the end of anesthesia, indicating a faster awakening of patients under xenon anesthesia. Blood pressure and heart rate indicators in the xenon group at the beginning and end of the study are not statistically significant compared to the sevoflurane group. Remaining indicators did not show significant differences between groups.</p> <p><bold>Conclusion</bold>. The use of sevoflurane and xenon during general anesthesia in outpatient dental practice characterized by the stability of the acid-base state, ion composition, and glucose concentration allows adequate conditions for spontaneous ventilation with pressure support. However, a faster awakening of the patient at the end was observed when using xenon. Diastolic blood pressure and heart rate in the xenon group after the end of anesthesia are close to baseline values.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение.</bold> Выбор оптимального анестетика в амбулаторной стоматологической практике — важнейший этап составления плана лечения детям, которым необходима санация полости рта в условиях общей анестезии. Работ посвященных сравнительной характеристике севофлурана и ксенона мало.</p> <p><bold>Цель</bold> — сравнить эффекты ингаляционной анестезии ксеноном и севофлураном на этапе поддержания анестезии в амбулаторной стоматологической практике.</p> <p><bold>Материалы и методы. </bold>В рандомизированное, контролируемое, в параллельных группах со случайной выборкой исследование включено 103 пациента обоих полов в возрасте от 2 до 12 лет. Дети были разделены на 2 группы: 1-я группа (35 детей) — анестезия севофлураном, 2-я группа (68 детей) — анестезия ксеноном. В каждой группе и между группами на этапах анестезии мониторировали данные BIS-индекса, частоты сердечных сокращений, артериального давления, показателей вентиляции легких, глюкозы, кислотно-щелочного состояния и ионного состава венозной крови.</p> <p><bold>Результаты. </bold>Достоверные различия между группами были отмечены в значениях BIS-индекса на этапе завершения анестезии, свидетельствующие о более быстром пробуждении пациентов при анестезии ксеноном. Показатели артериального давления и частоты сердечных сокращений в группе ксенона исходно и в конце исследования статистически не значимы, по сравнению с группой севофлурана. Остальные показатели не имели значимых различий между группами.</p> <p><bold>Заключение. </bold>Использование севофлурана и ксенона при проведении общей анестезии в амбулаторной стоматологической практике характеризуется стабильностью кислотно-щелочного состояния, ионного состава, концентрации глюкозы, позволяет обеспечить адекватные условия для спонтанной вентиляции легких с аппаратной поддержкой давлением.</p></trans-abstract><kwd-group xml:lang="en"><kwd>xenon</kwd><kwd>children</kwd><kwd>sevoflurane</kwd><kwd>ambulatory anesthesia</kwd><kwd>dentistry</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ксенон</kwd><kwd>севофлуран</kwd><kwd>амбулаторная анестезия</kwd><kwd>стоматология</kwd><kwd>дети</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Raeder J, Gupta A, Pedersen FM. Recovery characteristics of sevoflurane- or propofol- based anesthesia for day-care surgery. 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