Russian Journal of Pediatric Surgery, Anesthesia and Intensive CareRussian Journal of Pediatric Surgery, Anesthesia and Intensive CareРоссийский вестник детской хирургии, анестезиологии и реаниматологии2219-40612587-6554Eco-Vector34210.17816/psaic342ReviewsОбзорыSHORT BOWEL SYNDROME IN CHILDRENСИНДРОМ КОРОТКОЙ КИШКИ У ДЕТЕЙSukhotnikI. G.СухотникИгорь Григорьевич
Israel

Профессор Израильского Института Технологии, Медицинский Факультет имени Руфи и Брюса Раппопорт, Кафедра детской хирургии, Медицинский Центр Бней-Цион, Хайфа, Израиль. Dept Pediatric Surgery B, BnaiZionMedicalCenter 47 Golomb St., P.O.B. 4940, Haifa, 31048, Israel. Ph (h): 972-4-8256815, Ph (b): 972-4-8359647, Fax-972-4-8359620.

igor-dr@internet-zahav.netThe Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Dept of Pediatric Surgery, Bnai Zion Medical CenterТехнион - Израильский Институт Технологии, Медицинский Факультет имени Руфи и Брюса Раппопорт, Кафедра детской хирургии, Медицинский Центр Бней-Цион1010201773981151010201710102017Copyright ©; 2017, Sukhotnik I.G.Copyright ©; 2017, Сухотник И.Г.2017Sukhotnik I.G.Сухотник И.Г.https://creativecommons.org/licenses/by-nc-nd/4.0https://rps-journal.ru/jour/article/view/342

Short bowel syndrome (SBS) continue to be important clinical problem in pediatric population due to high mortality and morbidity rates, as well as their devastating socioeconomic effects. In this paper, the etiology of SBS, its pathophysiology, the cellular and molecular mechanisms of intestinal adaptation, are reviewed. The most common complications of SBS are outlined with strategies to reduce them. The medical management and nutritional support of a patient with SBS is complex and requires a multidisciplinary. A review of the pharmacologic agents and growth factors that have been studied experimentally and administered clinically for the management of short bowel syndrome is presented. Surgical procedures to promote intestinal adaptation and intestinal lengthening have largely changed the available options for non-transplant interventions.

Синдром короткой кишки (СКК) – драматичный раздел хирургии детского возраста, характеризующийся высокой частотой тяжелых осложнений и летальных исходов, негативными социально-экономическими последствиями. В статье рассматриваются этиология и патофизиология синдрома короткой кишки, механизмы адаптации и терапии пациентов, наиболее распространенные осложнения, стратегия их предотвращения, значение междисциплинарного подхода. Представлен обзор фармакологических средств и факторов роста в аспекте экспериментальных исследований и клинической практики. Описаны технологии реконструктивных хирургических вмешательств и вариантов трансплантации кишечника.

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