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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский вестник детской хирургии, анестезиологии и реаниматологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4061</issn><issn publication-format="electronic">2587-6554</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">292</article-id><article-id pub-id-type="doi">10.17816/psaic292</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Study Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">INTRAOPERATIVE GLYCEMIC PROFILE AND DEMAND IN GLUCOSE IN NEWBORNS</article-title><trans-title-group xml:lang="ru"><trans-title>ИНТРАОПЕРАЦИОННЫЙ ГЛИКЕМИЧЕСКИЙ ПРОФИЛЬ И ПОТРЕБНОСТЬ В ГЛЮКОЗЕ У НОВОРОЖДЕННЫХ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nasser</surname><given-names>M. M.</given-names></name><name xml:lang="ru"><surname>Нассер</surname><given-names>Марианна Мохаммед Абдул Маджид</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Клинический ординатор по специальности анестезиология– реаниматология отделения хирургии и реанимации </p><p>врач-педиатр</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kucherov</surname><given-names>Yu. I.</given-names></name><name xml:lang="ru"><surname>Кучеров</surname><given-names>Юрий Иванович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Доктор медицинских наук, заведующий отделением хирургии и реанимации новорожденных</p><p>профессор кафедры детской хирургии</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zhirkova</surname><given-names>Yu. V.</given-names></name><name xml:lang="ru"><surname>Жиркова</surname><given-names>Юлия Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Доктор медицинских наук, главный научный сотрудник отделения хирургии и реанимации новорожденных</p><p>профессор кафедры детской анестезиологии и интенсивной терапии </p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Scientific Health Center for Children of the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Научный центр здоровья детей МЗ России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N. I. Pirogov Russian National Research Medical University of the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава России (Москва)</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-12-10" publication-format="electronic"><day>10</day><month>12</month><year>2016</year></pub-date><volume>6</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>57</fpage><lpage>62</lpage><history><date date-type="received" iso-8601-date="2017-06-10"><day>10</day><month>06</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-06-10"><day>10</day><month>06</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Nasser M.M., Kucherov Y.I., Zhirkova Y.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Нассер М.М., Кучеров Ю.И., Жиркова Ю.В.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Nasser M.M., Kucherov Y.I., Zhirkova Y.V.</copyright-holder><copyright-holder xml:lang="ru">Нассер М.М., Кучеров Ю.И., Жиркова Ю.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://rps-journal.ru/jour/article/view/292">https://rps-journal.ru/jour/article/view/292</self-uri><abstract xml:lang="en"><p>The article sums up the data of the study examining the intraoperative glycemic status in 30 newborns with congenital abnormalities. Median age at the operation amounted to 72 [48; 168] years of life, duration of surgery was 72.5 [60; 90] minutes. All children used general anesthesia (Sevofluran+ Phentanyl), intraoperative infusion therapy consisted of saline solutions. The level of glucose in blood was estimated before the surgery, every 30 minutes during the surgery and at the end of the surgery; correction was performed when needed. High frequency of non-euglycemic conditions was revealed especially at the stages of tracheal intubation and skin incision. In the majority of cases the children had hypoglycemia (66.7%) requiring correction. During the surgery, the blood glucose level was normalized and remained within the reference range. Thus, intraoperative glycemia in newborns is an unstable indicator; it requires monitoring for adequate infusion of glucose-containing solutions to avoid hypo- and hyperglycemia. </p></abstract><trans-abstract xml:lang="ru"><p>В статье приведены данные исследования интраоперационного гликемического статуса у 30 новорожденных с врожденными пороками развития. Возраст на момент операции составил Ме 72 [48; 168] часов жизни, длительность операции 72,5 [60; 90] минут. Всем детям проводилась общая анестезия (севофлюран+фентанил), интраоперационная инфузионная терапия состояла из солевых растворов. Уровень сахара в крови оценивали до операции, во время операции каждые 30 минут и в конце хирургического вмешательства, при необходимости проводили коррекцию. Выявлена высокая частота встречаемости не-эугликемических состояний, особенно на этапах интубации трахеи и разреза кожи. В большинстве случаев у детей наблюдалась гипогликемия (66,7%), требующая коррекции. В ходе операции уровень сахара крови нормализовывался и оставался в пределах референтных значений. Т.о., интраоперационная гликемия у новорожденных является нестабильным показателем и требует проведения мониторинга для адекватной инфузии глюкозосодержащих растворов с целью избежания гипо- и гипергликемии. </p></trans-abstract><kwd-group xml:lang="en"><kwd>anesthesia</kwd><kwd>intraoperative infusion therapy</kwd><kwd>newborns</kwd><kwd>glycaemia</kwd><kwd>hypoglycemia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>анестезия</kwd><kwd>интраоперационная инфузионная терапия</kwd><kwd>новорожденные</kwd><kwd>гликемия</kwd><kwd>гипогликемия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. McCann M. E., Schouten A. N. 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