Russian Journal of Pediatric Surgery, Anesthesia and Intensive CareRussian Journal of Pediatric Surgery, Anesthesia and Intensive Care2219-40612587-6554Eco-Vector23010.17816/psaic230THE MORPHOLOGICAL CHARACTERISTICS OF THE BIOPSY IN CHILDREN WITH SPINAL DYSRAPHISMShamsievA. M.internetnirvana@gmail.comAliyevB. P.noemail@neicon.ruNikolaevS. N.snik.2011@mail.ruBaibekovI. M.noemail@neicon.ruShamsievJ. A.noemail@neicon.ruSamarkand State Medical Institute2th Clinic of Samarkand State Medical InstituteThe Pirogov Russian National Research Medical University3001201661384630012017Copyright © 2016, Shamsiev A.M., Aliyev B.P., Nikolaev S.N., Baibekov I.M., Shamsiev J.A.2016Biopsies of removed spina bifida and regional tissue in 21 children (before the age of 1 year) who were operated on meningoradiculocele and 18 biopsies in combination with congenital intradural malformations were exposed to morphological study. Retrospective analysis of histological features of the various forms of spina bifida identified an objective assessment of expediency of different methods of surgical treatment according to the form of malformation. The results showed that skin covering the area of all forms of spina bifida is characterized by distinct polymorphism. At the same time the specific changes of epidermis were not found in the various forms of spina bifida. The often result of operations, which were conducted outside of a specialized agency, is aggravation of the disintegration and demyelization processes caused by secondary arachnoid, soft and dura mater adhesions, greater involvement of the spinal cord pathways and roots in the adhesions, severe disorders of local hemodynamics.спинно-мозговая грыжадемиелинизациябиопсияспинальные тканевые мальформацииspina bifidademyelizationbiopsyspinal tissue malformations[Волкова О. В., Пекарский М. И. Эмбриогенез и возрастная гистология внутренних органов человека. - М.: Медицина, 1976. С. 416.][Кривощеков В. Д. Патология вертебрального канала: Диагностика и лечение: автореф. канд. мед. наук. Пермь. 1993. С. 138.][Лепеев А. Ф. Хирургическое лечение сочетанных врожденных мальформаций каудальных отделов позвоночника и спинного мозга у детей: автореф. дис…..канд. мед. наук. - М., 1998. С. 25.][Мажейко Л. И. Экстравертебральные проявления дизонтогенетических изменений позвоночника у детей // Вертебрология. 1992. № 1. С. 26-29.][Никифоров Б. М., Смирнов Г. И., Диденко Э. В. Диастематомиелия позвоночника в сочетании с дермоидной опухолью конского хвоста // Педиатрия. 1972. № 7. С. 81-82.][Хачатрян В. А., Орлов Ю. А., Осипов И. Б., Еликбаев Г. М. Спинальные дизрафии - Спб.: Десятка. С. 303.][Anderson F. M. Occult spinal dysraphism: diagnosis and management // J. Pediatr. 1968. V. 73. P. 163-177.][Bauer S. B. Early evaluation and management of children with spina bifida // King L. R. (ed). Urologic surgery in neonates and young infants. Philadelphia: WB Saunders, 1988. P. 252-264.]