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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский вестник детской хирургии, анестезиологии и реаниматологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4061</issn><issn publication-format="electronic">2587-6554</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1948</article-id><article-id pub-id-type="doi">10.17816/psaic1948</article-id><article-id pub-id-type="edn">BOENUO</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Study Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Is stoma always required in patients with Crohn disease undergoing ileocecal resection in the setting of a psoas abscess? A case series</article-title><trans-title-group xml:lang="ru"><trans-title>Всегда ли необходима стома у пациентов с болезнью Крона и илеоцекальной резекцией на фоне псоас-абсцесса? Серия клинических случаев</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>伴腰大肌脓肿的克罗恩病患者行回盲部切除术是否必须造口？临床病例系列</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-4768-1539</contrib-id><contrib-id contrib-id-type="spin">8703-3966</contrib-id><name-alternatives><name xml:lang="en"><surname>Glushkova</surname><given-names>Victoria A.</given-names></name><name xml:lang="ru"><surname>Глушкова</surname><given-names>Виктория Александровна</given-names></name><name xml:lang="zh"><surname>Glushkova</surname><given-names>Victoria A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>pedsurgspb@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6006-9112</contrib-id><contrib-id contrib-id-type="spin">7052-0205</contrib-id><name-alternatives><name xml:lang="en"><surname>Podkamenev</surname><given-names>Aleksey V.</given-names></name><name xml:lang="ru"><surname>Подкаменев</surname><given-names>Алексей Владимирович</given-names></name><name xml:lang="zh"><surname>Podkamenev</surname><given-names>Аleksey V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Assistant Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine), Assistant Professor</p></bio><email>av.podkamenev@gpmu.org</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7931-2263</contrib-id><contrib-id contrib-id-type="spin">2853-5956</contrib-id><name-alternatives><name xml:lang="en"><surname>Gabrusskaya</surname><given-names>Tatyana V.</given-names></name><name xml:lang="ru"><surname>Габрусская</surname><given-names>Татьяна Викторовна</given-names></name><name xml:lang="zh"><surname>Gabrusskaya</surname><given-names>Tatyana V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><email>tatyanagabrusskaya@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2487-0783</contrib-id><name-alternatives><name xml:lang="en"><surname>Shilova</surname><given-names>Elena V.</given-names></name><name xml:lang="ru"><surname>Шилова</surname><given-names>Елена Вадимовна</given-names></name><name xml:lang="zh"><surname>Shilova</surname><given-names>Elena V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>komarova_lena@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saint Petersburg State Pediatric Medical University</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский государственный педиатрический медицинский университет</institution></aff><aff><institution xml:lang="zh">Saint Petersburg State Pediatric Medical University</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2025</year></pub-date><volume>15</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>527</fpage><lpage>537</lpage><history><date date-type="received" iso-8601-date="2025-08-23"><day>23</day><month>08</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-11-10"><day>10</day><month>11</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2025,</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://rps-journal.ru/jour/article/view/1948">https://rps-journal.ru/jour/article/view/1948</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND:</bold> In the presence of a penetrating or stricturing–penetrating phenotype of Crohn disease, the formation of a psoas abscess is possible. Ileocecal resection is the most common surgical procedure for complicated Crohn disease. The feasibility of performing an anastomosis in the presence of a psoas abscess remains controversial. The lack of clear management algorithms for Crohn disease with psoas abscess and the rarity of this condition in pediatric patients determine the relevance of the present study.</p> <p><bold>AIM:</bold><bold> </bold>To evaluate treatment outcomes and the necessity of stoma formation in patients with complicated Crohn disease undergoing ileocecal resection in the setting of a psoas abscess.</p> <p><bold>METHODS:</bold> The study included data from 8 patients with complicated Crohn’s disease who underwent ileocecal resection in the setting of a psoas abscess. In 6 of 8 patients (75%), no stoma was formed, whereas the remaining patients underwent a two-stage procedure with stoma creation. Intestinal anastomosis was constructed manually using an end-to-end two-layer technique. Broad-spectrum antibacterial therapy was administered preoperatively in 7 of 8 patients (87.5%) for 7–14 days, with a positive clinical and laboratory response.</p> <p><bold>RESULTS:</bold> In half of the patients, the abscess size did not exceed 3 cm, and this group received conservative antibacterial therapy prior to surgery. In 2 patients, the abscess was detected intraoperatively and surgical sanitation was performed. Before ileocecal resection, 7 of 8 patients did not receive glucocorticosteroid therapy; only 1 patient received a minimal dose of prednisolone (5 mg). Partial parenteral nutrition and albumin transfusion for nutritional correction were required in 4 of 8 patients (50%) for 7–14 days. Infectious complications occurred in 4 of 8 patients (50%) and were superficial in nature, not exceeding Grade I on the Clavien–Dindo classification.</p> <p><bold>CONCLUSION:</bold> The presence of a psoas abscess is a potential risk factor for intestinal anastomotic failure but is not a reliable predictor of an unfavorable surgical outcome. When a psoas abscess is identified prior to planned ileocecal resection, conservative treatment or percutaneous drainage is recommended (depending on abscess size), with clinical response assessment over 5–7 days (resolution of fever and reduction in inflammatory laboratory markers). In such cases, we consider primary intestinal anastomosis feasible within 7–14 days.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование.</bold> При наличии пенетрирующего или стриктурирующего и пенетрирующего фенотипа болезни Крона возможно формирование псоас-абсцесса. Илеоцекальная резекция — это наиболее частое оперативное вмешательство при осложненных формах болезни Крона. Вопрос о возможности формирования анастомоза на фоне псоас-абсцесса является дискутабельным. Отсутствие четких алгоритмов по ведению пациентов с псоас-абсцессом при болезни Крона и редкость патологии в детском возрасте обусловливают актуальность данного исследования.</p> <p><bold>Цель. </bold>Оценить результаты лечения, необходимость формирования стомы у пациентов с осложненной формой болезни Крона и выполнением илеоцекальной резекции на фоне псоас-абсцесса.</p> <p><bold>Методы.</bold> В исследование включены данные 8 пациентов с осложненной формой болезни Крона, которым была выполнена илеоцекальная резекция на фоне псоас-абсцесса. У 6 из 8 (75%) пациентов стому не накладывали, остальным выполнено двухэтапное лечение с формированием стомы. Кишечный анастомоз выполняли ручным способом, «конец в конец», двухрядным швом. Антибактериальную терапию препаратами широкого спектра действия проводили 7 из 8 пациентов (87,5%) до операции от 7 до 14 дней с положительным клинико-лабораторным ответом.</p> <p><bold>Результаты. </bold>У каждого второго пациента размер абсцесса не превышал 3 см и перед хирургическим этапом эта группа пациентов получала консервативное лечение в виде антибактериальной терапии. У 2 пациентов абсцесс был выявлен интраоперационно, выполнена хирургическая санация. У 7 из 8 пациентов перед проведением резекции илеоцекальной зоны терапия глюкокортикостероидами отсутствовала, у единственного пациента она составляла минимальные значения в виде 5 мг преднизолона. Частичное парентеральное питание и трансфузия альбумина с целью коррекции нутритивного статуса потребовались у половины пациентов (4/8 пациентов — 50%), которые проводили в сроки от 7 до 14 дней. Уровень инфекционных осложнений у 4 из 8 пациентов (50%) носил характер поверхностных и не превышал по шкале послеоперационных осложнений (Clavien–Dindo) значения 1.</p> <p><bold>Заключение.</bold> Наличие псоас-абсцесса — один из факторов возможной несостоятельности кишечного анастомоза, но не достоверный предиктор неблагоприятного исхода хирургического вмешательства. При выявлении псоас-абсцесса до планируемой илеоцекальной резекции (в зависимости от размеров абсцесса) рекомендуется проведение его консервативного лечения или чрескожного дренирования с оценкой клинического ответа в течение 5–7 дней (купирование лихорадки, снижение воспалительной лабораторной активности), в таких случаях считаем возможным выполнение первичного кишечного анастомоза через 7–14 дней.</p></trans-abstract><trans-abstract xml:lang="zh"><p><bold>论证。</bold>在穿透型或狭窄合并穿透型克罗恩病患者中，可能形成腰大肌脓肿。回盲部切除术是复杂克罗恩病最常见的手术方式。在合并腰大肌脓肿的情况下是否能够实施肠道吻合仍存在争议。由于目前缺乏克罗恩病合并腰大肌脓肿患者的明确处理方案，且该病在儿童中较为罕见，因此本研究具有现实意义。</p> <p><bold>目的。</bold>评估合并腰大肌脓肿背景下行回盲部切除术的克罗恩病患者的治疗结果及是否需要造口。</p> <p><bold>方法。</bold>本研究纳入8例 接受腰大肌脓肿背景下回盲部切除术的复杂克罗恩病患者。在8例患者中，有6例（75%）未行造口术，其余患者接受了分期手术并行造口术。所有肠道吻合均采用手工端对端双层缝合。在8例患者中，有7例（87.5%）在术前接受了为期7–14天的广谱抗菌药物治疗，并获得了积极的临床及实验室反应。</p> <p><bold>结果。</bold>有一半患者腰大肌脓肿直径不超过3 cm，且在手术前该组患者均接受了以抗菌药物为主的保守治疗。2例患者脓肿于术中发现并行手术清创。在行回盲部切除术前，8例患者中有7例未接受糖皮质激素治疗，仅1例患者以最低剂量使用泼尼松5 mg。8例患者中有4例（50%）因营养状态不良接受部分肠外营养及白蛋白输注，治疗持续7–14天。8例患者中有4例（50%）发生术后感染性并发症，均为表浅感染，按Clavien–Dindo术后并发症分级不超过 I 级。</p> <p><bold>结论。</bold>腰大肌脓肿是肠道吻合口可能发生不全的因素之一，但并非不良结局的确定性预测指标。若在择期回盲部切除术前发现腰大肌脓肿（视其大小而定），建议先行抗菌治疗或经皮引流，并于5–7天内评估临床反应（退热、炎症指标下降）。在此情况下，7–14天后实施一期肠道吻合是可行的。</p></trans-abstract><kwd-group xml:lang="en"><kwd>Crohn disease</kwd><kwd>children</kwd><kwd>psoas abscess</kwd><kwd>anastomotic leakage</kwd><kwd>case series</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>болезнь Крона</kwd><kwd>дети</kwd><kwd>псоас-абсцесс</kwd><kwd>несостоятельность анастомоза</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>克罗恩病</kwd><kwd>儿童</kwd><kwd>腰大肌脓肿</kwd><kwd>吻合口不全</kwd><kwd>临床病例</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Ullrich SJ, Frischer JS. Surgical management of complicated Crohn’s disease. Semin Pediatr Surg. 2024;33(2):151399. doi: 10.1016/j.sempedsurg.2024.151399</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Collard MK, Benoist S, Maggiori L, et al. A reappraisal of outcome of elective surgery after successful non-operative management of an intra-abdominal abscess complicating ileocolonic Crohn’s disease: A subgroup analysis of a nationwide prospective cohort. J Crohns Colitis. 2021;15(3):409–418. doi: 10.1093/ecco-jcc/jjaa217</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Orscheln ES, Dillman JR, Towbin AJ, et al. Penetrating Crohn disease: does it occur in the absence of stricturing disease? Abdom Radiol. 2018;43(7):1583–1589. doi: 10.1007/s00261-017-1398-7</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Lightner AL, Vogel JD, Carmichael JC, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the surgical management of Crohn’s disease. Dis Colon Rectum. 2020;63(8):1028–1052. doi: 10.1097/DCR.0000000000001716</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Kornienko EA, Khavkin AI, Fedulova EN, et al. Draft recommendations of the russian society of pediatric gastroenterology, hepatology and nutrition on diagnosis and treatment of Crohn’s disease in children. Experimental and Clinical Gastroenterology. 2019;(11):100–134. doi: 10.31146/1682-8658-ecg-171-11-100-134 EDN: CFTALD</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Levine A, Griffiths A, Markowitz J, et al. Pediatric modification of the Montreal classification for inflammatory bowel disease: The Paris classification. Inflamm Bowel Dis. 2011;17(6):1314–1321. doi: 10.1002/ibd.21493</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Ghoneima AS, Flashman K, Dawe V, et al. High risk of septic complications following surgery for Crohn’s disease in patients with preoperative anaemia, hypoalbuminemia and high CRP. Int J Colorectal Dis. 2019;34(12):2185–2188. doi: 10.1007/s00384-019-03427-7</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Versteegh HP, Huijgen D, Meeussen CJHM, et al. A Complicated matter: Predictors for postoperative infections after bowel resection in pediatric inflammatory bowel disease. J Pediatr Surg. 2025;60(3):162105. doi: 10.1016/j.jpedsurg.2024.162105</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Gutiérrez A, Rivero M, Martín-Arranz MD, et al. Perioperative management and early complications after intestinal resection with ileocolonic anastomosis in Crohn’s disease: analysis from the PRACTICROHN study. Gastroenterol Rep. 2019;7(3):168–175. doi: 10.1093/gastro/goz010</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Celentano V, Giglio MC, Pellino G, et al. High complication rate in Crohn’s disease surgery following percutaneous drainage of intra-abdominal abscess: a multicentre study. Int J Colorectal Dis. 2022;37(6):1421–1428. doi: 10.1007/s00384-022-04183-x</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Sakurai Kimura CM, Scanavini Neto A, Queiroz NSF, et al. Abdominal surgery in Crohn’s disease: Risk factors for complications. Inflamm Intest Dis. 2021;6(1):18–24. doi: 10.1159/000510999</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Kavalukas SL, Scheurlen KM, Galandiuk S. State-of-the-art surgery for Crohn’s disease: Part I—small intestine/ileal disease. Langenbecks Arch Surg. 2022;407(3):885–895. doi: 10.1007/s00423-021-02324-4</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Adamina M, Minozzi S, Warusavitarne J, et al. ECCO guidelines on therapeutics in Crohn’s disease: Surgical treatment. J Crohns Colitis. 2024;18(10):1556–1582. doi: 10.1093/ecco-jcc/jjae089</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Guo K, Ren J, Li G, et al. Risk factors of surgical site infections in patients with Crohn’s disease complicated with gastrointestinal fistula. Int J Colorectal Dis. 2017;32(5):635–643. doi: 10.1007/s00384-017-2751-6</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Bemelman WA, Warusavitarne J, Sampietro GM, et al. ECCO-ESCP consensus on surgery for Crohn’s disease. J Crohns Colitis. 2018;12(1):1–16. doi: 10.1093/ecco-jcc/jjx061</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Pfefferkorn MD, Marshalleck FE, Saeed SA, et al. NASPGHAN clinical report on the evaluation and treatment of pediatric patients with internal penetrating Crohn disease: intraabdominal abscess with and without fistula. J Pediatr Gastroenterol Nutr. 2013;57(3):394–400. doi: 10.1097/MPG.0b013e31829ef850</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Casas Deza D, Polo Cuadro C, De Francisco R, et al. Initial management of intra-abdominal abscesses and preventive strategies for abscess recurrence in penetrating Crohn’s disease: A national, multicentre study based on ENEIDA registry. J Crohns Colitis. 2024;18(4):578–588. doi: 10.1093/ecco-jcc/jjad184</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Feagins LA, Holubar SD, Kane SV, Spechler SJ. Current strategies in the management of intra-abdominal abscesses in Crohn’s disease. Clin Gastroenterol Hepatol. 2011;9(10):842–850. doi: 10.1016/j.cgh.2011.04.023</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Dotson JL, Bashaw H, Nwomeh B, Crandall WV. Management of intra-abdominal abscesses in children with Crohn's disease: A 12-year, retrospective single-center review. Inflamm Bowel Dis. 2015;21(5):1109–1114. doi: 10.1097/MIB.0000000000000361</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Waked B, Holvoet T, Geldof J, et al. Conservative management of spontaneous intra‐abdominal abscess in Crohn’s disease: Outcome and prognostic factors. J Dig Dis. 2021;22(5):263–270. doi: 10.1111/1751-2980.12984</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>El-Hussuna A, Karer MLM, Uldall Nielsen NN, et al. Postoperative complications and waiting time for surgical intervention after radiologically guided drainage of intra-abdominal abscess in patients with Crohn’s disease. BJS Open. 2021;5(5):zrab075. doi: 10.1093/bjsopen/zrab075</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Bouguen G, Huguet A, Amiot A, et al. Efficacy and safety of tumor necrosis factor antagonists in treatment of internal fistulizing Crohn’s disease. Clin Gastroenterol Hepatol. 2020;18(3):628–636. doi: 10.1016/j.cgh.2019.05.027</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Levin A, Risto A, Myrelid P. The changing landscape of surgery for Crohn’s disease. Semin Colon Rectal Surg. 2020;31(2):100740. doi: 10.1016/j.scrs.2020.100740</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Neary PM, Aiello AC, Stocchi L, et al. High-risk ileocolic anastomoses for Crohn’s disease: When is diversion indicated? J Crohns Colitis. 2019;13(7):856–863. doi: 10.1093/ecco-jcc/jjz004</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Glenisson M, Bonnard A, Berrebi D, et al. Complications and disease recurrence after ileocecal resection in pediatric Crohn’s disease: A Retrospective study. Eur J Pediatr Surg. 2024;34(3):253–260. doi: 10.1055/a-2048-7407</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Shcherbakova OV, Shumilov PV. Postoperative complications in children with Crohn’s disease: an analysis of risk predictors. Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care. 2022;12(3):301–310. doi: 10.17816/psaic1284 EDN: QXOVYY</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Hashash JG, Elkins J, Lewis JD, Binion DG. AGA clinical practice update on diet and nutritional therapies in patients with inflammatory bowel disease: Expert review. Gastroenterology. 2024;166(3):521–532. doi: 10.1053/j.gastro.2023.11.303</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Sangster W, Berg AS, Choi CS, et al. Outcomes of early ileocolectomy after percutaneous drainage for perforated ileocolic Crohn’s disease. Am J Surg. 2016;212(4):728–734. doi: 10.1016/j.amjsurg.2016.01.044</mixed-citation></ref></ref-list></back></article>
