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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский вестник детской хирургии, анестезиологии и реаниматологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4061</issn><issn publication-format="electronic">2587-6554</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1895</article-id><article-id pub-id-type="doi">10.17816/psaic1895</article-id><article-id pub-id-type="edn">EDAQMK</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Suppurative Pyelonephritis in a Newborn with Congenital Urinary Tract Malformation: Diagnostic Challenges and Management Approach: a Case Report</article-title><trans-title-group xml:lang="ru"><trans-title>Гнойно-деструктивный пиелонефрит у новорожденного с врожденным пороком развития мочевой системы: трудности диагностики и тактика ведения. Клинический случай</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>伴泌尿系统先天畸形新生儿的化脓性破坏性肾盂肾炎： 诊断难点与治疗策略。临床病例</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5957-7037</contrib-id><contrib-id contrib-id-type="spin">7990-4317</contrib-id><name-alternatives><name xml:lang="en"><surname>Kuzovleva</surname><given-names>Galina I.</given-names></name><name xml:lang="ru"><surname>Кузовлева</surname><given-names>Галина Игоревна</given-names></name><name xml:lang="zh"><surname>Kuzovleva</surname><given-names>Galina I.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Medicine)</p></bio><email>dr.gala@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-3716-7958</contrib-id><contrib-id contrib-id-type="spin">3885-4085</contrib-id><name-alternatives><name xml:lang="en"><surname>Zhurina</surname><given-names>Anastasia A.</given-names></name><name xml:lang="ru"><surname>Журина</surname><given-names>Анастасия Александровна</given-names></name><name xml:lang="zh"><surname>Zhurina</surname><given-names>Anastasia A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>zhurina.nastenka@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-0770-3457</contrib-id><name-alternatives><name xml:lang="en"><surname>Kondratenko</surname><given-names>Ekaterina D.</given-names></name><name xml:lang="ru"><surname>Кондратенко</surname><given-names>Екатерина Дмитриевна</given-names></name><name xml:lang="zh"><surname>Kondratenko</surname><given-names>Ekaterina D.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>kondratenko.ekaterina2000@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7861-6778</contrib-id><contrib-id contrib-id-type="spin">5560-6679</contrib-id><name-alternatives><name xml:lang="en"><surname>Zhirkova</surname><given-names>Julia V.</given-names></name><name xml:lang="ru"><surname>Жиркова</surname><given-names>Юлия Викторовна</given-names></name><name xml:lang="zh"><surname>Zhirkova</surname><given-names>Julia V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine)</p></bio><email>zhirkova@mail.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7189-373X</contrib-id><contrib-id contrib-id-type="spin">4391-4472</contrib-id><name-alternatives><name xml:lang="en"><surname>Kucherov</surname><given-names>Yuri I.</given-names></name><name xml:lang="ru"><surname>Кучеров</surname><given-names>Юрий Иванович</given-names></name><name xml:lang="zh"><surname>Kucherov</surname><given-names>Yuri I.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine)</p></bio><email>Ykucherov@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6137-2359</contrib-id><name-alternatives><name xml:lang="en"><surname>Kondratenko</surname><given-names>Natalia V.</given-names></name><name xml:lang="ru"><surname>Кондратенко</surname><given-names>Наталия Владимировна</given-names></name><name xml:lang="zh"><surname>Kondratenko</surname><given-names>Natalia V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>KondratenkoNV@zdrav.mos.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-5403-3452</contrib-id><name-alternatives><name xml:lang="en"><surname>Funk</surname><given-names>Valeria A.</given-names></name><name xml:lang="ru"><surname>Функ</surname><given-names>Валерия Андреевна</given-names></name><name xml:lang="zh"><surname>Funk</surname><given-names>Valeria A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>funk_lera@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2892-4665</contrib-id><contrib-id contrib-id-type="spin">5307-4320</contrib-id><name-alternatives><name xml:lang="en"><surname>Eremeeva</surname><given-names>Alina V.</given-names></name><name xml:lang="ru"><surname>Еремеева</surname><given-names>Алина Владимировна</given-names></name><name xml:lang="zh"><surname>Eremeeva</surname><given-names>Alina V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Associate Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine), Associate Professor</p></bio><email>alinaeremeeva@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Sechenov First Moscow State Medical University</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет им. И.М. Сеченова</institution></aff><aff><institution xml:lang="zh">Sechenov First Moscow State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Speransky Children’s City Clinical Hospital No. 9</institution></aff><aff><institution xml:lang="ru">Детская городская клиническая больница № 9 им. Г.Н. Сперанского</institution></aff><aff><institution xml:lang="zh">Speransky Children’s City Clinical Hospital No. 9</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution></aff><aff><institution xml:lang="zh">Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-07-04" publication-format="electronic"><day>04</day><month>07</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-07-15" publication-format="electronic"><day>15</day><month>07</month><year>2025</year></pub-date><volume>15</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>269</fpage><lpage>278</lpage><history><date date-type="received" iso-8601-date="2025-01-29"><day>29</day><month>01</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-06-01"><day>01</day><month>06</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2025,</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://eco-vector.com/for_authors.php#07</ali:license_ref></license></permissions><self-uri xlink:href="https://rps-journal.ru/jour/article/view/1895">https://rps-journal.ru/jour/article/view/1895</self-uri><abstract xml:lang="en"><p>Purulent kidney lesions occupy a special place in pediatric practice, yet only isolated or small series of cases have been reported to date. This paper presents a clinical case of a 12-day-old patient admitted with lethargy, feeding refusal, fever, and depressed consciousness. Epidemiological history revealed prolonged household contact with varicella. Examination revealed enlargement of the right kidney with multiple diffuse focal changes in the parenchyma, enlargement of the left kidney, multiple microabscesses, signs of ureterohydronephrosis, and bladder wall thickening. Surgical revision of the right kidney was performed via a translumbar approach, with placement of a subcapsular drain and insertion of a cystostomy. The patient received antibacterial, antiviral, and infusion therapy, along with immunological support. Discharge from hospital occurred on day 32 of admission. At follow-up, at the age of 5 months, the Foley cystostomy catheter was removed, and a universal 5Ch ureteral stent was placed in the left ureter, which was removed at 6 months. This clinical case of suppurative pyelonephritis in a newborn with a congenital urinary tract malformation demonstrates the need for staged treatment and formation of a multidisciplinary team of specialists — neonatologists, pediatric surgeons, pediatric urologists, nephrologists, and clinical pharmacologists — for timely diagnosis and successful management.</p></abstract><trans-abstract xml:lang="ru"><p>Гнойные поражения почек занимают особое место в педиатрической практике, до настоящего времени описаны лишь единичные случаи или серии случаев. В статье представлено клиническое наблюдение пациента 12 дней жизни, поступившего с жалобами на вялость, отказ от еды, лихорадку, угнетение сознания. В данных по эпидемиологическому анамнезу — длительный контакт по дому с ветряной оспой. При обследовании больного выявлено увеличение размеров правой почки со множественными диффузно-очаговыми изменениями паренхимы; увеличение размеров левой почки; множественные апостемы, признаки уретерогидронефроза, утолщение стенок мочевого пузыря. Проведена ревизия правой почки транслюмбальным доступом с установкой дренажа в подкапсульную область почки, установлена цистостома. Пациент получил антибактериальную, противовирусную, инфузионную терапию и иммунологическую поддержку. Выписан из стационара на 32-е сутки госпитализации. При дальнейшем наблюдении в возрасте 5 мес. удален цистостомический катетер Фолея и выполнено стентирование левого мочеточника универсальным стентом 5Ch, который был удален в возрасте 6 мес. Приведенный клинический случай гнойно-деструктивного пиелонефрита у новорожденного с врожденным пороком развития мочевой системы демонстрирует необходимость этапного лечения с формированием мультидисциплинарной команды специалистов с включением неонатологов, детских хирургов, детских урологов, нефрологов, клинических фармакологов для своевременной диагностики и успешного лечения таких пациентов.</p></trans-abstract><trans-abstract xml:lang="zh"><p>肾脏的化脓性病变在儿科实践中占有特殊地位，现有文献多为个案或小样本系列报道。本文报告一例生后第12天因嗜睡、拒食、发热及意识障碍入院的患儿。流行病学史提示其在家中曾长期接触水痘患者。检查发现右肾增大，实质出现多发弥漫性灶性改变；左肾亦增大；多发性小脓肿形成；存在输尿管积水性肾炎表现；膀胱壁增厚。经腰后入路对右肾进行探查，于肾包膜下区置管引流，并建立膀胱造口。给予抗菌、抗病毒、输液及免疫支持治疗。住院第32天出院。后续随访中，患儿于5月龄时拔除膀胱造口导尿管，并置入左侧输尿管5Ch通用支架；6月龄时取出支架。该病例显示，对于合并泌尿系统先天畸形的新生儿化脓性破坏性肾盂肾炎，需采取分阶段治疗策略，并组建由新生儿科医生、儿科外科医生、儿科泌尿外科医生、肾脏病专家及临床药理学专家组成的多学科协作团队，以实现及时诊断与成功治疗。</p></trans-abstract><kwd-group xml:lang="en"><kwd>newborn</kwd><kwd>suppurative pyelonephritis</kwd><kwd>congenital urinary tract malformation</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>новорожденный</kwd><kwd>гнойно-деструктивный пиелонефрит</kwd><kwd>порок развития мочевой системы</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>新生儿</kwd><kwd>化脓性破坏性肾盂肾炎</kwd><kwd>泌尿系统畸形</kwd><kwd>诊断</kwd><kwd>治疗</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Pieretti RV, Pieretti-Vanmarcke R, Pieretti A. 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