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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский вестник детской хирургии, анестезиологии и реаниматологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4061</issn><issn publication-format="electronic">2587-6554</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1571</article-id><article-id pub-id-type="doi">10.17816/psaic1571</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Study Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Comparative analysis of the results of multispiral computed tomography using color mapping and magnetic resonance imaging in the diagnosis of acute hematogenous osteomyelitis in children</article-title><trans-title-group xml:lang="ru"><trans-title>Сравнительный анализ результатов мультиспиральной компьютерной томографии с использованием методов цветового картирования и магнитно-резонансной томографии в диагностике острого гематогенного остеомиелита у детей</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>多螺旋计算机断层扫描彩色图谱与磁共振成像在诊断儿童急性血源性骨髓炎髓内阶段中的结果对比分析</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1110-066X</contrib-id><contrib-id contrib-id-type="spin">1000-6408</contrib-id><name-alternatives><name xml:lang="en"><surname>Pozdnyakov</surname><given-names>Alexander V.</given-names></name><name xml:lang="ru"><surname>Поздняков</surname><given-names>Александр Владимирович</given-names></name><name xml:lang="zh"><surname>Pozdnyakov</surname><given-names>Alexander V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Med.), Professor</p></bio><email>pozdnyakovalex@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0126-3190</contrib-id><contrib-id contrib-id-type="spin">7684-9637</contrib-id><name-alternatives><name xml:lang="en"><surname>Svarich</surname><given-names>Vyacheslav G.</given-names></name><name xml:lang="ru"><surname>Сварич</surname><given-names>Вячеслав Гаврилович</given-names></name><name xml:lang="zh"><surname>Svarich</surname><given-names>Vyacheslav G.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Med.)</p></bio><email>svarich61@mail.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8818-0055</contrib-id><contrib-id contrib-id-type="spin">2687-8324</contrib-id><name-alternatives><name xml:lang="en"><surname>Lyurov</surname><given-names>Denis A.</given-names></name><name xml:lang="ru"><surname>Лыюров</surname><given-names>Денис Алексеевич</given-names></name><name xml:lang="zh"><surname>Lyurov</surname><given-names>Denis A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>denis_liurov@mail.ru</email><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff5"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saint Petersburg State Pediatric Medical University</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский государственный педиатрический медицинский университет</institution></aff><aff><institution xml:lang="zh">Saint Petersburg State Pediatric Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Republican Children’s Clinical Hospital</institution></aff><aff><institution xml:lang="ru">Республиканская детская клиническая больница</institution></aff><aff><institution xml:lang="zh">Republican Children’s Clinical Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Pitirim Sorokin Syktyvkar State University</institution></aff><aff><institution xml:lang="ru">Сыктывкарский государственный университет им. Питирима Сорокина</institution></aff><aff><institution xml:lang="zh">Pitirim Sorokin Syktyvkar State University</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Republican Children’s Hospital</institution></aff><aff><institution xml:lang="ru">Республиканская детская клиническая больница</institution></aff><aff><institution xml:lang="zh">Republican Children’s Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">Pitirim Sorokin Syktyvkar state University</institution></aff><aff><institution xml:lang="ru">Сыктывкарский государственный университет им. Питирима Сорокина</institution></aff><aff><institution xml:lang="zh">Pitirim Sorokin Syktyvkar state University</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2023-12-18" publication-format="electronic"><day>18</day><month>12</month><year>2023</year></pub-date><pub-date date-type="pub" iso-8601-date="2023-12-20" publication-format="electronic"><day>20</day><month>12</month><year>2023</year></pub-date><volume>13</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>503</fpage><lpage>511</lpage><history><date date-type="received" iso-8601-date="2023-11-13"><day>13</day><month>11</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-11-26"><day>26</day><month>11</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2023,</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://rps-journal.ru/jour/article/view/1571">https://rps-journal.ru/jour/article/view/1571</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND</bold><italic>:</italic> Although acute hematogenous osteomyelitis is considered a fairly well-studied disease, several articles emphasize that the frequency of diagnostic errors remains quite high. The clinical presentation of acute hematogenous osteomyelitis largely depends on its reactivity and localization. The latter has features of the clinical course in children of different age groups. Osteomyelitis can be difficult to detect because of the variability and nonspecificity of symptoms and physical and laboratory parameters. Rapid diagnosis is crucial for successful disease outcomes because untimely treatment increases the number of complications. Therefore, visualization should be aimed at early diagnosis and, ultimately, successful treatment.</p> <p><bold>AIM</bold><italic>:</italic> This study aimed to evaluate the informative value of magnetic resonance imaging and multispiral computed tomography (MSCT) in the diagnosis of the intramedullary phase of acute hematogenous osteomyelitis as its earliest stage.</p> <p><bold>MATERIALS AND METHODS</bold><italic>:</italic> Thirty patients suspected with acute hematogenous osteomyelitis underwent magnetic resonance imaging and MSCT using color mapping techniques and X-ray density assessment. At the final stage of the diagnostic algorithm, osteotonometry was performed. The contents of the bone marrow canal were taken for microbiological and bacteriological studies.</p> <p><bold>RESULTS</bold><italic>:</italic> In the intramedullary phase of acute hematogenous osteomyelitis, magnetic resonance imaging and MSCT revealed signs of bone marrow edema in 96% of the cases. The sensitivity of magnetic resonance imaging was 96%, the same as that of MSCT; however, the specificity was significantly lower than that of MSCT using the color mapping method and X-ray density assessment, which was 67% and 83%, respectively (<italic>p </italic>&lt; 0.05).</p> <p><bold>DISCUSSION</bold><italic>:</italic> In recent years, the role of computed tomography in the diagnosis of acute hematogenous osteomyelitis has received considerable recognition in pediatric surgical practice, and MSCT with color mapping and X-ray density assessment in the diagnosis of acute hematogenous osteomyelitis in children has been used relatively recently. Simultaneously, many researchers have reported the high informativeness of MSCT in the diagnosis of acute hematogenous osteomyelitis.</p> <p><bold>CONCLUSIONS</bold><italic>:</italic> The intramedullary phase of acute hematogenous osteomyelitis according to magnetic resonance imaging and MSCT indicates bone marrow edema as its earliest stage. According to the data of the present study, MSCT using color mapping and X-ray density assessment has high specificity and can be used with MRI as the main method for diagnosing the intramedullary phase of acute hematogenous osteomyelitis.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Актуальность</bold>. Несмотря на то что острый гематогенный остеомиелит считается достаточно хорошо изученным заболеванием, частота диагностических ошибок остается достаточно высокой. Остеомиелит бывает трудно выявить из-за вариабельности и неспецифичности симптомов, физикальных и лабораторных показателей. Ранняя диагностика имеет решающее значение для успешного исхода заболевания, так как несвоевременное лечение увеличивает количество осложнений.</p> <p><bold>Цель</bold> — оценить информативность методов магнитно-резонансной томографии и мультиспиральной компьютерной томографии в диагностике интрамедуллярной фазы острого гематогенного остеомиелита, как его наиболее раннего признака.</p> <p><bold>Материалы и методы</bold>. Тридцати пациентам с подозрением на острый гематогенный остеомиелит были выполнены магнитно-резонансная томография и мультиспиральная компьютерная томография с применением методики цветного картирования и оценкой рентгеновской плотности. На заключительном этапе диагностического алгоритма проводили остеотонометрию. Одновременно производили забор содержимого костно-мозгового канала для проведения микробиологических и бактериологических исследований.</p> <p><bold>Результаты</bold>. В интрамедуллярной фазе острого гематогенного остеомиелита при магнитно-резонансной томографии и мультиспиральной компьютерной томографии в 96 % случаев выявлены признаки отека костного мозга. Чувствительность магнитно-резонансной томографии составила 96 %, так же как и при мультиспиральной компьютерной томографии, однако специфичность была значительно ниже, чем у мультиспиральной компьютерной томографии с применением метода цветового картирования и оценкой рентгенологической плотности, и составила соответственно 67 % против 83 % (<italic>p</italic> &lt; 0,05).</p> <p><bold>Обсуждение</bold>. В последние годы роль компьютерной томографии в диагностике острого гематогенного остеомиелита у детей получила значительное признание в детской хирургической практике, а использование мультиспиральной компьютерной томографии с применением метода цветового картирования и оценкой рентгенологической плотности в диагностике острого гематогенного остеомиелита у детей стало использоваться относительно недавно. В то же время о высокой информативности мультиспиральной компьютерной томографии в диагностике острого гематогенного остеомиелита сообщалось многими исследователями.</p> <p><bold>Выводы</bold>. 1. Картина интрамедуллярной фазы острого гематогенного остеомиелита по данным магнитно-резонансной томографии и мультиспиральной компьютерной томографии свидетельствует об отеке костного мозга, как его наиболее раннем признаке. 2. По данным настоящего исследования, мультиспиральная компьютерная томография с использованием метода цветового картирования и оценкой рентгеновской плотности обладает высокой специфичностью и может совместно с магнитной резонансной томографией использоваться в качестве основного метода диагностики интрамедуллярной фазы острого гематогенного остеомиелита.</p></trans-abstract><trans-abstract xml:lang="zh"><p><bold>论证</bold>。尽管急性血源性骨髓炎被认为是一种研究相当深入的疾病，但诊断错误的发生率仍然相当高。由于症状、体征和实验室检查结果的多变性和非特异性，骨髓炎很难被发现。早期诊断对疾病的成功结局至关重要，因为治疗不及时会增加并发症的数量。</p> <p><bold>目的</bold>。本研究旨在评估磁共振成像和多螺旋计算机断层扫描方法在诊断急性血源性骨髓炎髓内期最早征兆方面的信息量。</p> <p><bold>材料与方法</bold>。30名疑似急性血源性骨髓炎患者接受了磁共振成像和多螺旋计算机断层扫描，并进行了彩色绘图和X射线密度评估。在诊断算法的最后阶段，还进行了骨密度测量。同时，采集骨髓管内容物进行微生物学和细菌学研究。</p> <p>结果。在急性血源性骨髓炎的髓内阶段，96%的病例通过磁共振成像和多螺旋计算机断层扫描发现骨髓水肿迹象。我们注意到，磁共振成像的灵敏度为96%，多螺旋计算机断层扫描的灵敏度相同，但特异性明显低于多螺旋计算机断层扫描彩色图谱和放射学密度评估，分别为67%和83%（P&lt;0.05）。</p> <p><bold>讨论</bold>。近年来，计算机断层扫描在诊断儿童急性血源性骨髓炎中的作用已在儿科外科实践中得到相当程度的认可，而在诊断儿童急性血源性骨髓炎中使用多螺旋计算机断层扫描并结合彩色图谱和放射学密度评估的应用则相对较晚。与此同时，许多研究人员都报道了多螺旋计算机断层扫描在诊断急性血源性骨髓炎中的高信息价值。</p> <p><bold>结论</bold>。1.磁共振成像和多螺旋计算机断层扫描显示，急性血源性骨髓炎髓内期的最早表现为骨髓水肿。</p> <p>2.根据本研究，多螺旋计算机断层扫描彩色图谱和X射线密度估算具有较高的特异性，可与磁共振成像共同作为诊断急性血源性骨髓炎髓内期的主要方法。</p></trans-abstract><kwd-group xml:lang="en"><kwd>multispiral computed tomography</kwd><kwd>magnetic resonance imaging</kwd><kwd>acute hematogenous osteomyelitis</kwd><kwd>intramedullary phase</kwd><kwd>diagnostics</kwd><kwd>children</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>мультиспиральная компьютерная томография</kwd><kwd>магнитно-резонансная томография</kwd><kwd>острый гематогенный остеомиелит</kwd><kwd>интрамедуллярная фаза</kwd><kwd>диагностика</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>多螺旋计算机断层扫描</kwd><kwd>磁共振成像</kwd><kwd>急性血源性骨髓炎</kwd><kwd>髓内期</kwd><kwd>诊断</kwd><kwd>儿童</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Shamsiev ZhA, Shamsiev AM, Makhmudov ZM. 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