EPIDEMIOLOGY OF AN ACUTE HEPATIC INJURY IN CHILDREN

Cover Page


Cite item

Full Text

Abstract

The article is devoted to an important issue of pediatric resuscitation such as acute kidney injury (AKI). A retrospective study of 245 patients with AKI was carried out. It was found out that the majority of patients were three years old. The causes of AKI were analyzed. In the entire group of patients the majority of causes were of renal nature. Meanwhile, the hemolytic-uremic syndrome (HUS) was the main cause of AKI in children. Children of different age had different causes and frequencies of AKI. The most serious population of patients suffered from AKI was represented by one-month-old babies. 

About the authors

A. L. Muzurov

M.F.Vladimirsky Moscow Regional Research Clinical Institute;

Author for correspondence.
Email: al_muz@mail.ru

Кандидат медицинских наук, заведующий отделением

доцент кафедры анестезиологии, реаниматологии и токсикологии детского возраста 

Russian Federation

D. V. Zverev

Children’s Municipal Clinical Hospital of Saint Vladimir of Moscow Health Department

Email: fake@neicon.ru

Кандидат медицинских наук, заведующий Центром гравитационной хирургии крови и гемодиализа

Russian Federation

T. Yu. Abaseeva

M.F.Vladimirsky Moscow Regional Research Clinical Institute

Email: fake@neicon.ru
Кандидат медицинских наук, старший научный сотрудник отделения детского диализа и гемокоррекции Russian Federation

G. A. Generalova

Children’s Municipal Clinical Hospital of Saint Vladimir of Moscow Health Department

Email: fake@neicon.ru
Кандидат медицинских наук, врач Russian Federation

T. E. Pankratenko

M.F.Vladimirsky Moscow Regional Research Clinical Institute

Email: fake@neicon.ru
Кандидат медицинских наук, заведующая отделением детского диализа и гемокоррекции Russian Federation

H. M. Emirova

A.I. Evdokimov Moscow State Medical and Dental University of the Ministry of Health of Russia

Email: fake@neicon.ru

Кандидат медицинских наук, доцент кафедры педиатрии

Russian Federation

O. M. Orlova

A.I. Evdokimov Moscow State Medical and Dental University of the Ministry of Health of Russia

Email: fake@neicon.ru
Ассистент кафедры педиатрии Russian Federation

M. V. Kvaratskhelia

Children’s Municipal Clinical Hospital of Saint Vladimir of Moscow Health Department;
A.I. Evdokimov Moscow State Medical and Dental University of the Ministry of Health of Russia

Email: fake@neicon.ru

Кандидат медицинских наук, врач

ассистент кафедры педиатрии

Russian Federation

A. I. Makulova

Children’s Municipal Clinical Hospital of Saint Vladimir of Moscow Health Department;
Pirogov Russian National Research Medical University of the Ministry of Health of Russia

Email: fake@neicon.ru

Кандидат медицинских наук, врач

доцент кафедры педиатрии 

Russian Federation

A. V. Popa

Children’s Municipal Clinical Hospital of Saint Vladimir of Moscow Health Department

Email: fake@neicon.ru
Кандидат медицинских наук, врач Russian Federation

References

  1. Сhertow G. M., Levy E. M., Hammermeister K. M., Grover F., Daley J. Independent association between acute renal failure and mortality following cardiac surgery. Am J Med 1998; 104: 343–348.
  2. Mendonca A., Vincent J. L., Suter P. M., Moreno R., Dearden N. M., Antonelli M., Takala J., Sprung C., Cantraine F. Acute renal failure in the ICU: Risk factors and outcome evaluated by the SOFA score. Intens Care Med 2000;26:915–921.
  3. Vivino G., Antonelli M., Moro M., Cottini F., Conti G., Bufi M., Cannata F., Gasparetto A. Risk factors for acute renal failure in trauma patients. Intens Care Med 1998; 24:808–814.
  4. Garg A. X., Suri R. S., Barrowman N. Long-term renal prognosis of diarrhea-associated hemolytic uremic syndrome: a systematic review, meta-analysis, and meta-regression. JAMA. 2003 Sep 10;290 (10):1360–70.
  5. Bellomo R., Ronco C., Kellum J. A., Mehta R. L., Palevsky P. Acute Dialysis Quality Initiative workgroup. Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care.2004 Aug; 8 (4):R204–12.
  6. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Inter. Suppl. 2012; Issue 1: 1–126.
  7. Mehta R. L., Kellum J. A., Shah S. V., Molitoris B. A., RoncoC., Warnock D. G., LevinA.Acute Kidney Injury Network. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007;11 (2):R31.
  8. Akcan-Arikan A., Zappitelli M., Loftis L. L., Washburn K. K., Jefferson L. S., Goldstein S. L. Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int. 2007 May; 71 (10):1028–35.
  9. Ricci Z., Ronco C. Neonatal RIFLE. Nephrol Dial Transplant. 2013 Sep;28 (9):2211–4.
  10. Schwartz G. J., Furth S. L. Glomerular filtration rate measurement and estimation in chronic kidney disease. PediatrNephrol.2007 Nov; 22 (11):1839–48.
  11. George J. Schwartz, Alvaro Munoz, Michael F. Schneider, Robert H. Mak, Frederick Kaskel, Bradley A. Warady, and Susan L. Furth. New Equations to Estimate GFR in Children with CKD. J Am SocNephrol20: 629–637, 2009.
  12. Khan O. A., Hageman J. R., Clardy C. Acute Renal Failure in the Neonate. Pediatr Ann. 2015 Oct;44 (10):e251–3.
  13. Sanjeev Gulati. Acute kidney injury in children. Nephrology 0101 (2012) 103–108.
  14. MacDonald C., Norris C., Alton G. Y., Urschel S. Acute kidney injury after heart transplant in young children: risk factors and outcomes. Pediatr Nephrol. 2016 Apr;31 (4):671–8.
  15. Tóth R., Breuer T., Cserép Z. Acute kidney injury is associated with higher morbidity and resource utilization in pediatric patients undergoing heart surgery. Ann Thorac Surg. 2012 Jun;93 (6):1984–90.
  16. Prodhan P., McCage L. S., Stroud M. H. Acute kidney injury is associated with increased in-hospital mortality in mechanically ventilated children with trauma. J Trauma Acute Care Surg. 2012 Oct;73 (4):832–7.
  17. Gómez Polo J. C., Alcaraz Romero A. J., Gil-Ruíz Gil-Esparza M. A. Morbimortality associated to acute kidney injury in patients admitted to pediatric intensive care units. Med Intensiva. 2014 Oct;38 (7):430–7.
  18. Slater M. B., Anand V., Uleryk E. M., Parshuram C. S.A systematic review of RIFLE criteria in children, and its application and association with measures of mortality and morbidity. Kidney Int. 2012 Apr;81 (8):791–8.
  20. Werner H., Buder K., Landolt M. A., Neuhaus T. J., Laube G. F., Spartà G. Long-term health-related quality of life and psychological adjustment in children after haemolytic-uraemic syndrome. Pediatr Nephrol. 2016 Dec 23.
  21. Riyuzo M. C., Silveira L. V., Macedo C. S., Fioretto J. R. Predictive factors of mortality in pediatric patients with acute renal injury associated with sepsis.J Pediatr.2017 Jan – Feb;93 (1):28–34.
  22. Fitzgerald J. C., Basu R. K., Akcan-Arikan A. Sepsis PRevalence, OUtcomes, and Therapies Study Investigators and PediatricAcute Lung Injury and Sepsis Investigators Network. Acute Kidney Injury in Pediatric Severe Sepsis: An Independent Risk Factor for Death and New Disability.Crit Care Med. 2016 Dec;44 (12):2241–2250.
  23. Greenberg J. H., Coca S., Parikh C. R. Long-termrisk of chronic kidney disease and mortality in children after acute kidney injury: a systematic review.BMC Nephrol. 2014 Nov 21;15:184.
  24. Askenazi D. J. Do children with acute kidney injury require long-term evaluation for CKD?Am J Kidney Dis. 2012 Apr;59 (4):478–80.
  25. Mammen С. et al. Long-term Risk of CKD in Children Surviving Episodes of Acute Kidney Injury in the Intensive Care Unit: A Prospective Cohort Study. Am J Kidney Dis. 2012;59 (4):52.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2017 Muzurov A.L., Zverev D.V., Abaseeva T.Y., Generalova G.A., Pankratenko T.E., Emirova H.M., Orlova O.M., Kvaratskhelia M.V., Makulova A.I., Popa A.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: ПИ № ФС 77 - 81892 от 24.09.2021 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies