STRUCTURAL CHANGES IN THE INTESTINAL WALL IN IMPLEMENTATION OF THE SYNDROME OF INTESTINAL DYSMOTILITY IN CHILDREN WITH GASTROSCHISIS

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Abstract

The authors presented the results of histopathological and immunohistochemical studies using autopsy material (22 newborns who died of gastroschisis). According to the results, in all the cases inflammation of the parietal and visceral peritoneum were of productive, proliferative and fibroplastic origin. In the majority of cases, an acute purulent inflammation with formation of abscesses at the level of the eviscerated intestinal loops was revealed.

In some cases the acute inflammation process was manifested through leukocytic erosive and abscessed inflammatory exudative fibrinous lesions at the level of the parietal and visceral peritoneum involving the entire intestinal wall in the process. The presence of only one mainly circular muscular layer was a peculiar feature found in the eviscerated intestinal loops with the external muscular layer undergoing regional hypoplasia or aplasia.

Results of the conducted study helped the authors to determine the combination of neuromuscular structural changes of the eviscerated intestinal loops and find the relation of the implementation of the intestinal motility stable disturbances in newborns with gastroschisis. 

About the authors

S. Babuch

Nikolai Testemitsanu State University of Medicine & Pharmacy

Author for correspondence.
Email: babuci@newmail.ru
Доктор медицинских наук, доцент, ведущий научный сотрудник лаборатории «Хирургическая инфекция у детей» кафедры детской хирургии, ортопедии и анестезиологии Moldova, Republic of

K. Tika

Ovidius University, Constanta

Email: tica.constantin@yahoo.com
медицинских наук, профессор, заведующий кафедрой детской хирургии Romania

V. Petrovich

Public Health Establishment the Institute of Mother and Child

Email: petrovicivergil@yahoo.com
Кандидат медицинских наук, старший научный сотрудник, заведующий отделением патологической анатомии Moldova, Republic of

L. Sinitsina

Public Health Establishment the Institute of Mother and Child

Email: lily10feb@rambler.ru
Кандидат медицинских наук, доцент, зав. научного отдела морфопатологии Moldova, Republic of

A. Zhalbe

Nikolai Testemitsanu State University of Medicine & Pharmacy

Email: sandujalba@gmail.com
Кандидат медицинских наук, доцент, кафедра детской хирургии, ортопедии и анестезиологии Moldova, Republic of

I. Negru

Nikolai Testemitsanu State University of Medicine & Pharmacy

Email: ionnegru@yahoo.com
Заведующий отделением гнойной хирургии, аспирант кафедры детской хирургии, ортопедии и анестезиологии Moldova, Republic of

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Copyright (c) 2016 Babuch S., Tika K., Petrovich V., Sinitsina L., Zhalbe A., Negru I.

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