ETIOLOGY AND PATHOPHYSIOLOGY OF CHRONIC INTESTINAL PSEUDO-OBSTRUCTIVE SYNDROM IN CHILDREN. PART I. INTESTINAL MOTILITY PHYSIOLOGY

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Abstract

Chronic intestinal pseudo-obstruction (CIPO) is a rare syndrome characterized by dilatation of the bowel lumen and abnormal motility in which no mechanical cause is identified. The syndrome appears at the background of congenital or acquired neuropathy, myopathy, or neuromyopathy. The article discusses the specifics of aetiopathogenesis of different disease forms, including de nova mutations discovered during the last decade. The article may be interested for surgeons who must be able to detect intestinal pseudo-obstruction to avoid unnecessary surgical interventions and also for other specialists who may encounter the syndrome in their practice.

About the authors

Yu. V. Averyanova

Russian Children's Clinical Hospital of the Russian Ministry of Healthcare

Author for correspondence.
Email: a10276j@yandex.ru
Russian Federation

A. Yu. Razumovsky

The Pirogov Russian National Research Medical University

Email: 1595105@mail.ru
Russian Federation

A. E. Stepanov

Russian Children's Clinical Hospital of the Russian Ministry of Healthcare

Email: operacia@rdkb.ru
Russian Federation

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Copyright (c) 2016 Averyanova Y.V., Razumovsky A.Y., Stepanov A.E.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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