The use of indocyanine green navigation in the treatment of a choledochal cyst in a child

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Abstract

In pediatric surgery, near-infrared fluorescence imaging using indocyanine green has become widespread. This report presents a new approach for intraoperative identification of extrahepatic bile duct anatomy during laparoscopic choledochal cyst resection and hepatoduodenostomy formation in a pediatric patient. A 10-month-old girl presented with episodes of restlessness accompanied by vomiting. On prenatal ultrasound, a cystic lesion was detected in the hepatic portal region, and its presence was subsequently confirmed on postnatal imaging. Contrast-enhanced computed tomography and magnetic resonance cholangiopancreatography revealed a Todani type Ib choledochal cyst measuring 2.2×1.6×1.6 cm. For intraoperative fluorescence navigation, indocyanine green (0.25 mg/kg) was administered intravenously 12 hours before surgery. The procedure consisted of laparoscopic cyst resection followed by hepatoduodenostomy creation. Operative time was 120 minutes. Fluorescence imaging clearly delineated the distal margin of the cyst within the pancreatic parenchyma and its proximal extent at the level of the common hepatic duct. Enteral feeding was initiated on postoperative day 2. No intraoperative complications occurred. Postoperatively, the patient showed improvement, with decreased bilirubin levels and liver enzyme activity. No evidence of anastomotic leakage was found during early follow-up. Hospital stay was 7 days. At 6 months of follow-up, the patient had no clinical or laboratory signs of obstructive jaundice or cholangitis. In conclusion, fluorescence imaging with indocyanine green is a safe and highly informative method for intraoperative identification and resection of a choledochal cyst.

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About the authors

Yury A. Kozlov

Irkutsk State Regional Children’s Clinical Hospital; Irkutsk State Medical Academy of Postgraduate Education—a branch of the Russian Medical Academy of Continuous Professional Education; Irkutsk State Medical University

Email: yuriherz@hotmail.com
ORCID iD: 0000-0003-2313-897X
SPIN-code: 3682-0832

MD, Dr. Sci. (Medicine), Professor, Corresponding Member of the Russian Academy of Sciences

Russian Federation, Irkutsk; Irkutsk; Irkutsk

Alexander P. Rozhanski

Irkutsk State Regional Children’s Clinical Hospital; Irkutsk State Medical University

Author for correspondence.
Email: alexanderozhanski@mail.ru
ORCID iD: 0000-0001-7922-7600
SPIN-code: 4012-7120

MD

Russian Federation, Irkutsk; Irkutsk

Marina V. Makarochkina

Irkutsk State Regional Children’s Clinical Hospital

Email: makarochkina@igodkb.ru
ORCID iD: 0000-0001-8295-6687
SPIN-code: 4600-4071

MD

Russian Federation, Irkutsk

Eduard V. Sapukhin

Irkutsk State Regional Children’s Clinical Hospital

Email: sapukhin@yandex.ru
ORCID iD: 0000-0001-5470-7384

MD

Russian Federation, Irkutsk

Alexey S. Strashinsky

Irkutsk State Regional Children’s Clinical Hospital

Email: leksus-642@yandex.ru
ORCID iD: 0000-0002-1911-4468
SPIN-code: 9210-5286

MD

Russian Federation, Irkutsk

Anna O. Ryakhina

Irkutsk State Regional Children’s Clinical Hospital

Email: romahka@yandex.ru
ORCID iD: 0009-0006-0340-1186

MD

Russian Federation, Irkutsk

Yulia P. Semshchikova

Irkutsk State Medical University

Email: jsemshikova@mail.ru
ORCID iD: 0000-0001-9049-0450

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, Irkutsk

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Supplementary files

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2. Fig. 1. Magnetic resonance cholangiopancreatography showing the choledochal cyst.

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3. Fig. 2. Stages of the surgical procedure: a, view of the common bile duct cyst at the beginning of the procedure; b, dissection of the distal portion of the choledochal cyst and clipping; c, view of the common hepatic duct after resection of the choledochal cyst; d, final view of the hepatoduodenostomy.

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